G Protein-Coupled Receptors as Potential Intercellular Communication Mediators in Trypanosomatidae
Detection and transduction of environmental signals, constitute a prerequisite for successful parasite invasion; i.e., Leishmania transmission, survival, pathogenesis and disease manifestation and dissemination, with diverse molecules functioning as ...
Emilia Díaz +7 more
doaj +1 more source
Die Peptide CGRP, Adrenomedullin und PTHrP bewirken eine Dilatation der Koronargefäße durch Aktivierung von KATP-Kanälen. [PDF]
CGRP, Adrenomedullin und PTHrP sind seit Mitte der 80er Jahre als vasoaktive Peptide bekannt. Bisher wurden Untersuchungen über die gefäßerweiternde Wirkung dieser Substanzen nur an Zellen oder nicht-isolierten Organen durchgeführt.
Gerhardus, Jan, Prof. Dr. Dr. Daut
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Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation. [PDF]
Receptor activity-modifying protein 2 (Ramp2) is a single-pass transmembrane protein that heterodimerizes with several family B G-protein coupled receptors to alter their function.
Mahita Kadmiel +4 more
doaj +1 more source
A guide to chemokines and their receptors [PDF]
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G‐protein coupled heptahelical chemokine receptors.
Braun A +11 more
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Intermedin attenuates LPS-induced inflammation in the rat testis [PDF]
First reported as a vasoactive peptide in the cardiovascular system, intermedin (IMD), also known as adrenomedullin 2 (ADM2), is a hormone with multiple potent roles, including its antioxidant action on the pulmonary, central nervous, cardiovascular and ...
Huang, C +6 more
core +5 more sources
Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma [PDF]
Serum protein fingerprints associated with MGUS and MM and their changes in MM after autologous stem cell transplantation (MM-ASCT, day 100) remain unexplored.
Fillerová, Regina +9 more
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The Calcitonin/Calcitonin Gene-Related Peptide Family in Invertebrate Deuterostomes
Calcitonin (CT)/CT gene-related peptide (CGRP) family peptides (CT/CGRP family peptides) including CT, CGRP, adrenomedullin, amylin, and CT receptor-stimulating peptide have been identified from various vertebrates and perform a variety of important ...
Toshio Sekiguchi
doaj +1 more source
Sacubitril/valsartan:beyond natriuretic peptides [PDF]
Natriuretic peptides, especially B-type natriuretic peptide (BNP), have primarily been regarded as biomarkers in heart failure (HF). However, they are also possible therapeutic agents due to potentially beneficial physiological effects.
Atlas +48 more
core +2 more sources
Multiple Receptor Subtypes for the CGRP Super-Family
Molecular evidence for the existence of multiple receptors for CGRP has been rather difficult to obtain. Over 10 years after suggesting the existence of at least two classes (CGRP1 and CGRP2) of CGRP receptors on the basis of pharmacological data[1 ...
R. Quirion +2 more
doaj +1 more source
VE-cadherin is an essential adhesion molecule in endothelial adherens junctions, and the integrity of these complexes is thought to be regulated by VE-cadherin tyrosine phosphorylation.
Romain Sigaud +14 more
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