Results 231 to 240 of about 45,405 (244)
Some of the next articles are maybe not open access.
Science Signaling, 2009
A distinctive family of proteins involved in the assembly of the most common excitatory brain receptor has been discovered.
openaire +2 more sources
A distinctive family of proteins involved in the assembly of the most common excitatory brain receptor has been discovered.
openaire +2 more sources
Stargazin and the AMPA receptor
Science, 2016Structural Biology AMPA-subtype ionotropic glutamate receptors (AMPARs) mediate fast excitatory neurotransmission and contribute to higher cognitive processes such as learning and memory. In the brain, AMPARs exist as protein-protein complexes with various auxiliary subunits that tightly control AMPAR trafficking, gating, and pharmacology.
openaire +2 more sources
The AMPA receptors of auditory neurons
Hearing Research, 2000The ionotropic glutamate receptor (GluR) subtype known as the AMPA receptor, which mediates rapid excitatory synaptic transmission in many regions of the nervous system, is composed of four different protein subunits, termed GluRs 1-4. The functional properties of each AMPA receptor are determined by the relative levels of GluRs 1-4 and by post ...
openaire +3 more sources
AMPA Receptor Trafficking and GluR1
Science, 2005In their Research Article “Postsynaptic receptor trafficking underlying a form of associative learning” (1 Apr., p. 83), S. Rumpel et al. draw the important conclusions that “encoding of memories in the lateral amygdala is mediated by AMPA receptor trafficking” and that “synaptic incorporation of AMPARs is necessary for learning.” The key experiment ...
openaire +3 more sources
European Journal of Pharmacology, 1996
A series of (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) analogues were evaluated for activity at homo-oligomeric glutamate1-flop (Glu1-flop) receptors expressed in Xenopus oocytes, using the two-electrode voltage clamp technique.
Wahl, P +4 more
openaire +3 more sources
A series of (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) analogues were evaluated for activity at homo-oligomeric glutamate1-flop (Glu1-flop) receptors expressed in Xenopus oocytes, using the two-electrode voltage clamp technique.
Wahl, P +4 more
openaire +3 more sources
Photocontrol of AMPA Receptors with a Photochromic Ligand
2014Photochromic ligands (PCLs), recently introduced by our group as a tool for researchers in neuroscience, offer the ability to control native receptors with light in a reversible fashion without the need for any genetic manipulation. Here we describe the application of the PCL Azo-Tetrazole-AMPA-3 (ATA-3) to reversibly gate native AMPA-receptors with ...
Martin Sumser, Philipp Stawski
openaire +3 more sources
Neurology, 2016
In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
openaire +3 more sources
In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
openaire +3 more sources
A Photochromic Agonist of AMPA Receptors
Angewandte Chemie International Edition, 2012Stawski, P.; Sumser, M.; Trauner, D.
openaire +3 more sources
Neuropharmacology of AMPA and kainate receptors
Neuropharmacology, 1998David Bleakman, David Lodge
openaire +3 more sources