Results 71 to 80 of about 45,095 (165)

Calcium-Permeable AMPA Receptors in the Retina [PDF]

Frontiers in Molecular Neuroscience, 2011
The retina transforms light entering the eye into a sophisticated neural representation of our visual world. Specialized synapses, cells, and circuits in the retina have evolved to encode luminance, contrast, motion, and other complex visual features. Although a great deal has been learned about the cellular morphology and circuitry that underlies this
openaire   +4 more sources

Metabolism peritumorous zone and alteration AMPAand NMDA-glutamate receptors in the pathogenesis of gliomas of the cerebral hemispheres

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014
Examined 12 patients with gliomas of the big hemispheres of a brain. Used immunoenzyme method for semiquantitative determination of the level of autoantibodies to NR2A-subunit of NMDA- and GluR1-subunit of AMPA-receptors of glutamate.
V. N. Ochkolyas, G. V. Kataeva
doaj   +1 more source

Ligand-dependent opening of the multiple AMPA receptor conductance states: a concerted model.

PLoS ONE, 2015
Modulation of the properties of AMPA receptors at the post-synaptic membrane is one of the main suggested mechanisms underlying fast synaptic transmission in the central nervous system of vertebrates.
Ranjita Dutta-Roy, Christian Rosenmund, Stuart J Edelstein, Nicolas Le Novère   +3 more
doaj   +1 more source

Аlterationdegree of NMDA and AMPA receptors of glutamate in the pathogenesis of the disease and technological peculiarities of surgical treatment of the hemispheric glioma-swith the epileptic syndrome

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014
The development of effective approaches to the treatment of patients with symptomatic tumor epilepsy was determined by the level of our fundamental knowledge of the basic mechanisms of epileptogenesis on cellular and molecular level.
V. N. Ochkolyas, M. B. Volov
doaj   +1 more source

A novel therapeutic approach for treatment of catamenial epilepsy

Neurobiology of Disease, 2018
Many women with epilepsy experience perimenstrual seizure exacerbation, referred to as catamenial epilepsy. There is no effective treatment for this condition, proposed to result from withdrawal of neurosteroid-mediated effects of progesterone.
Suchitra Joshi, Huayu Sun, Karthik Rajasekaran, John Williamson, Edward Perez-Reyes, Jaideep Kapur   +5 more
doaj   +1 more source

Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses

eLife
Chemical synapses are the major sites of communication between neurons in the nervous system and mediate either excitatory or inhibitory signaling.
Aya Matsui, Cathy Spangler, Johannes Elferich, Momoko Shiozaki, Nikki Jean, Xiaowei Zhao, Maozhen Qin, Haining Zhong, Zhiheng Yu, Eric Gouaux   +9 more
doaj   +1 more source

Positive AMPA and Kainate Receptor Modulators and Their Therapeutic Potential in CNS Diseases: A Comprehensive Review. [PDF]

Int J Mol Sci
Vialko A, Chałupnik P, Szymańska E.
europepmc   +1 more source

Chronic reduction of synaptic proteins in the epileptogenic lesion of patients with hippocampal sclerosis. [PDF]

Front Mol Neurosci
Oota-Ishigaki A, Suzuki N, Iijima K, Takayama Y, Kimura Y, Hattori K, Iwasaki M, Hayashi T.   +7 more
europepmc   +1 more source

Mechanisms involved in corticotropin-releasing factor-induced excitation of entorhinal neurons and facilitation of glutamate release at the perforant pathway. [PDF]

J Neurophysiol
Oraegbuna CS, Kurada L, Li H, Lei S.
europepmc   +1 more source

Targeting Excitatory Glutamate Receptors for Morphine Tolerance: A Narrative Review. [PDF]

CNS Neurosci Ther
Huang M, Luo L, Wang W, Xu H, Chen M, Ma X, Xu T.   +6 more
europepmc   +1 more source