Results 61 to 70 of about 673,183 (288)
Transition between immune and disease states in a cellular automaton model of clonal immune response
, 1997 In this paper we extend the Celada-Seiden (CS) model of the humoral immune response to include infectious virus and cytotoxic T lymphocytes (cellular response).
Abbas +26 more
core +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
EBF1, PAX5, and MYC: regulation on B cell development and association with hematologic neoplasms
Frontiers in ImmunologyDuring lymphocyte development, a diverse repertoire of lymphocyte antigen receptors is produced to battle against pathogens, which is the basis of adaptive immunity.
Li Li, Daiquan Zhang, Xinmei Cao
doaj +1 more source
B cell antigen receptor signaling and internalization are mutually exclusive events.
PLoS Biology, 2006 Engagement of the B cell antigen receptor initiates two concurrent processes, signaling and receptor internalization. While both are required for normal humoral immune responses, the relationship between these two processes is unknown.
Ping Hou +8 more
doaj +1 more source
A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons
BMC Immunology, 2023 Background The anglerfish, belonging to the teleost order Lophiiformes, are a diverse and species-rich group of fish that are known to exhibit a number of unique morphological, reproductive and immunological adaptations.
Jeremy B. Swann +3 more
doaj +1 more source
Superantigen Recognition and Interactions: Functions, Mechanisms and Applications
Frontiers in Immunology, 2021 Superantigens are unconventional antigens which recognise immune receptors outside their usual recognition sites e.g. complementary determining regions (CDRs), to elicit a response within the target cell.
Anthony M. Deacy +3 more
doaj +1 more source
Molecular requirements of the B‐cell antigen receptor for sensing monovalent antigens
The EMBO Journal, 2016 How the B-cell antigen receptor (BCR) is activated upon interaction with its cognate antigen or with anti-BCR antibodies is not fully understood. We have recently shown that B-cell activation is accompanied by the opening of the pre-organized BCR oligomers, an observation that strengthens the role of receptor reorganization in signalling.
Naema Brings +10 more
openaire +5 more sources
, 1995 Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut +1 more
core +1 more source
Genomic donor cassette sharing during VLRA and VLRC assembly in jawless vertebrates
, 2014 Lampreys possess two T-like lymphocyte lineages that express either variable lymphocyte receptor (VLR) A or VLRC antigen receptors. VLRA+ and VLRC+ lymphocytes share many similarities with the two principal T-cell lineages of jawed vertebrates expressing
Aravind, L. +8 more
core +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source