Results 221 to 230 of about 15,411,883 (261)

T cell receptor positive T cells in the inflammatory joint: Lack of association with response to soluble antigens

Cellular Immunology, 1991
In patients with inflammatory synovitis, the proliferative response by lymphocytes from synovial fluid to soluble mycobacterial antigens is enhanced relative to those from peripheral blood. Earlier studies suggested that gamma/delta T cell receptor positive (TCR+) T lymphocytes may significantly contribute to the mycobacterial-specific synovial fluid ...
R M, Pope, A, Landay, R L, Modlin, J, Lessard, A E, Koch   +4 more
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Surface Expression of Two Distinct Functional Antigen Receptors on Human γδ T Cells

Science, 1993
Lymphocytes recognize antigens with highly variable heterodimeric surface receptors. Although four distinct antigen receptors could in principle be produced by any lymphocyte, only one functional combination of receptor chains has thus far been found expressed on their surface.
F, Davodeau, M A, Peyrat, I, Houde, M M, Hallet, G, De Libero, H, Vié, M, Bonneville   +6 more
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IL‐2‐Dependent Murine T‐Cell Lines and Clones Expressing Gamma/Delta T‐Cell Antigen Receptors. I, Functional and Biochemical Characterization

Scandinavian Journal of Immunology, 1991
We have developed two stable IL‐2‐dependenl T‐cell lines designated AKV‐I and AKV‐N from the enlarged spleens, respectively, of an AKV l and an NFS mouse, Immunofluorescence staining with the appropriate monoclonal antibodies revealed that cells of the AKV‐I cell line were αβJTCR‐CD3+CD4‐ CD5‐ CD8+CD25+. Where as cells of the AKV‐N cell line were αβTCR‐
J J, Morkowski, M, Nanno, P F, Chen, K, Itoh, C G, Ioannides, E, Kruzel, F F, Becker, C D, Platsoucas   +7 more
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Murine T cells with invariant gamma delta antigen receptors: origin, repertoire, and specificity.

Seminars in immunology, 1991
T cells bearing invariant gamma delta T cell antigen receptors localize to distinct epithelial sites in the adult mouse. These gamma delta T cells differ from the lymphoid alpha beta and gamma delta T cells in several ways. The epithelial gamma delta T cells appear to be the product of the earliest waves of TCR expressing cells in the fetal thymus ...
W L, Havran, A, Carbone, J P, Allison
openaire   +1 more source

Functional expression of CD28 on T cell antigen receptor γ/δ‐bearing T lymphocytes

European Journal of Immunology, 1989
AbstractT lymphocytes express a T cell antigen receptor (TcR) complex composed of either an TcR α/β or TcR γ/δ heterodimer in noncovalent association with the CD3 glycoproteins. CD28, a 44‐kDa disulfide‐linked homodimer, is present on the surface of the majority of TcR α/β‐bearing T lymphocytes.
R, Testi, L L, Lanier
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T cell receptor gamma delta repertoire is skewed in cerebrospinal fluid of multiple sclerosis patients: molecular and functional analyses of antigen-reactive gamma delta clones.

European journal of immunology, 1995
To study the relevance of gamma delta T cells in multiple sclerosis (MS) we analyzed the T cell receptor (TCR) gamma delta repertoire and the antigen reactivity of gamma delta clones isolated from cerebrospinal fluid (CSF). In T cell cultures derived from CSF we found an increased percentage of V delta 1+ cells as compared to peripheral blood of the ...
Nick S, Pileri P, Tongiani S, Uematsu Y, Kappos L, De Libero G   +5 more
openaire   +3 more sources

Transcriptional regulation of gamma/delta T cell antigen receptor.

Los linfocitos T gd juegan un papel esencial en la respuesta inmunitaria mediante la rápida producción de grandes cantidades de citoquinas, teniendo gran importancia en la respuesta inmunitaria frente a determinados patógenos y en la protección en determinados lugares anatómicos.
Rodríguez-Caparrós, Alonso, Taniichi, Shizue, López-Ros, Jennifer, Ruiz Rodríguez, Candela, López-Castellanos, Laura, Álvarez-Santiago, Jesús, Castro Ruiz, Víctor, García Mañas, Celia, Ikuta, Koichi, Hernández-Munaín, Cristina   +9 more
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T cells bearing gamma/delta T cell receptor and their expression of activation antigen in peripheral blood from patients with Sjögren's syndrome.

Clinical and experimental rheumatology, 1992
T cells bearing gamma/delta T cell receptor (gamma/delta + T cells) and their expression of activation antigen (HLA-DR) or the marker of natural killer (NK) cells (CD56), were examined in the peripheral blood lymphocytes (PBL) from twenty-two patients with Sjögren's syndrome (SS) by three-color flowcytometry to elucidate possible pathological roles of ...
Y, Ichikawa, H, Shimizu, M, Yoshida, M, Takaya, S, Arimori   +4 more
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379 Engineering of gamma/delta T cells derived from cord blood for chimeric antigen receptor-T cell therapies

Regular and Young Investigator Award Abstracts, 2022
Chelsia Qiuxia Wang, Alice Cheung, Andy Hee-Meng Tan   +2 more
openaire   +1 more source

Faculty Opinions recommendation of The immunobiology of T cells with invariant gamma delta antigen receptors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2022
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