Results 141 to 150 of about 712,184 (317)

Characterisation of bovine leukocyte Ig-like receptors

, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Laing Ken, Martin Vordermeier, John Trowsdale, Singh Mahavir, Philip Butcher (173962), Allen Rachel L., Ken Laing, Laing, K, Butcher, P, Mahavir Singh, Des C Jones, Butcher, Philip, Bhuju, S, Ken Laing (173955), Vordermeier, M, Singh, Mahavir, Jones, DC, Trowsdale, John, Mahavir Singh (70735), Rachel L Allen, Hogan, Louise, Trowsdale, J, Hogan Louise, Vordermeier Martin, Hogan, L, Philip Butcher, Singh, M, Allen, RL, Des C. Jones (173949), Louise Hogan (173942), John Trowsdale (1225), Martin Vordermeier (108962), Trowsdale John, Vordermeier, Martin, Allen, Rachel L, Jones Des C., Sabin Bhuju, Laing, Ken, Bhuju Sabin, Sabin Bhuju (107606), Rachel L. Allen (173972), Jones, Des C, Bhuju, Sabin, Louise Hogan, Butcher Philip   +44 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Therapeutic dendritic cell vaccination against human papillomavirus

, 2009
Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually.
Nurkkala Karlsson, Merja
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype

, 2012
Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs.
Kleuser, Burkhard (Prof. Dr. rer. nat.), Radeke, Heinfried H., Japtok, Lukasz, Heinfried H Radeke, Kleuser, Burkhard, Jeong, Se Kyoo, Wolfgang Bäumer, Burkhard Kleuser, Katrin Schaper, Heinfried H. Radeke, Schaper, Katrin, Lukasz Japtok, Bäumer, Wolfgang, Se Kyoo Jeong   +13 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chimeric antigen receptor T-cell therapy [PDF]

Indian Journal of Medical and Paediatric Oncology, 2020
Azgar Abdul Rasheed, Venkata Pradeep Babu Koyyala   +1 more
openaire   +1 more source

Regulatory T cell control of anti-tumour responses

, 2008
One of the main obstacles to immunotherapy of cancer in humans is the immunosuppressive environment that surrounds the tumour mass, preventing any effective immune response from halting or reversing the threat of the tumour. Thus the observations in Balb/
Malcolm, Timothy I.M.
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source