Results 251 to 260 of about 924,854 (308)

Lymphocyte function inhibition and exhaustion in sepsis: mechanisms and applications. [PDF]

Front Immunol
Yan Y, Wang J, Wang C, Tao X, Cheng P, Qin J, Niu B.   +6 more
europepmc   +1 more source

Potential of small-molecule targeted drugs in combination with CAR-T cell therapy for hematologic lymphomas. [PDF]

Front Immunol
Tang W, Yu S.
europepmc   +1 more source

CAR-T Cells: Current Status, Challenges, and Future Prospects. [PDF]

MedComm (2020)
Adly AS, Cartron G, Adly AS, Egea JC, Dutilleul PC, Adly MS, Villalba M.   +6 more
europepmc   +1 more source

Research progress on the molecular mechanisms of PD-1 and LAG-3 synergy in regulating T cell exhaustion and immunotherapy. [PDF]

Ann Med
Li M, Duan D, Liu C, Xiong Q.
europepmc   +1 more source

Lactate signaling and immune suppression in tumors: mechanisms and therapeutic implications. [PDF]

Cell Oncol (Dordr)
Wang X, Xiong D, Cui S, Duan B, Ding G, Huang Y, Wang Q.   +6 more
europepmc   +1 more source

Immune evasion of multidrug-resistant bacteria: insights from lung innate immune cells and targeted therapies. [PDF]

Front Cell Infect Microbiol
Xu Y, Gao Y, Li Y, Pan L.
europepmc   +1 more source

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Antigen-specific T cell receptors

1987
Publisher Summary This chapter discusses immunoglobulin-related T cell receptors. It also presents the production of antibodies to both antigen-binding T cell receptors that are known to be related to immunoglobulin variable regions and to the α/β heterodimers that do not bind antigen, but are encoded by rearranged genes showing sufficient homology ...
J J, Marchalonis, S F, Schluter
openaire   +2 more sources

T cell antigen receptor signal transduction

Current Opinion in Cell Biology, 1997
The T cell antigen receptor (TCR) initiates signal transduction by activating multiple cytoplasmic protein tyrosine kinases (PTKs). Considerable progress in the field of TCR signal transduction has been made in three areas recently: first, in understanding the structure and function of the PTK ZAP-70; second, in the elucidation of the function of the ...
D, Qian, A, Weiss
openaire   +2 more sources

T cell antigen receptor antibodies

Nature, 1987
Immunology has a long tradition of using the immune system to study the immune system. Monoclonal antibodies are now being focused upon the antigen receptor of the T lymphocyte.
openaire   +2 more sources

T cell antigen-receptor signal transduction

Current Opinion in Immunology, 1999
During the past year, major progress has been made in understanding proximal TCR signal-transduction events. Cbl has been identified as a negative regulator of kinases from the ZAP-70/Syk family. Studies on LAT, SLP-76, Itk and Vav have revealed their role in the activation of Ras and phospholipase-Cgamma1-Ca2+ signalling pathways.
J E, van Leeuwen, L E, Samelson
openaire   +2 more sources