Results 181 to 190 of about 26,165 (305)

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, Volume 36, Issue 44, 1 June 2026.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Conformational Dynamics of Amylin Receptors Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. [PDF]

J Am Chem Soc
Fairweather CJ, Zhang X, Fernando CD, Garama DJ, Sexton PM, Wootten D, Josephs TM.   +6 more
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Functional characterization of neuropeptides that act as ligands for both calcitonin-type and pigment-dispersing factor-type receptors in a deuterostome. [PDF]

Elife
Cong X, Liu H, Liu L, Escudero Castelán N, Jones KGE, Egertová M, Elphick MR, Chen M.   +7 more
europepmc   +1 more source

ESTELA‐Study: Long‐Term Effectiveness and Safety of Anti‐Calcitonin Gene‐Related Peptide Monoclonal Antibodies in Real‐World Clinical Practice

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Background Anti‐CGRP antibodies are effective and safe in real‐world migraine management, but guidelines recommend discontinuation after 12–18 months due to limited long‐term data and remaining uncertainties regarding optimal treatment duration and sustained safety, highlighting the need for large‐scale long‐term real‐world evidence.
Alba Somovilla, Iris Fernández‐Lázaro, Josué Pagán, Daniel Saiz, Javier Díaz‐De‐Terán, Leonardo Portocarrero Sánchez, Germán Latorre, Carlos Calle De Miguel, Nuria González‐García, María‐Luz Cuadrado, Jesús Porta‐Etessam, Javier Casas‐Limón, David Garcia‐Azorin, Ángel Guerrero‐Peral, Yésica González‐Osorio, Alicia Gonzalez‐Martinez, Guillermo Martín Ávila, Rodrigo Terrero Carpio, Jaime Rodríguez‐Vico, Alex Jaimes, Andrea Gómez García, Cristina Trevino‐Peinado, Margarita Sanchez‐Del‐Rio, Alberto Lozano Ros, Antonio Sánchez‐Soblechero, Sarai Urtiaga Valle, Marta González‐Salaices, Elena Riva, Ana Gago‐Veiga   +28 more
wiley   +1 more source

Calcitonin-secreting pancreatic neuroendocrine tumor: A case report and literature review. [PDF]

J Family Med Prim Care
Wang H, Li J, Wang Z, Hua S, Liao Q.
europepmc   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 100-112, June 2026.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, Volume 67, Issue 6, Page 2689-2706, June 2026.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source

Neuro-immune interactions in urticaria:a pruritus-centric dissection. [PDF]

Front Immunol
Ke C, Ma N, Chen G, Yao Y, Ji J, Jiao Q.
europepmc   +1 more source