Results 101 to 110 of about 9,580 (229)

Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells

, 2023
The integrity of retinal endothelial cell (EC) is essential for establishing and maintaining the retinal blood barrier to ensure proper vision. Vitamin D is a hormone with known protective roles in EC function.
Yong-Seok Song, Christine M. Sorenson, Nader Sheibani, Nasim Jamali   +3 more
core   +1 more source

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

JOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody, Emma M. Wade, Shuji Mizumoto, Jeremy McCallum‐Loudeac, Megan J. Wilson   +4 more
wiley   +1 more source

Recent advances in intravenous calcitriol treatment

, 1994
Ten years after the pioneering data by Slatopolsky, there is growing evidence that calcitriol given intravenously is able to improve secondary hyperparathyroidism better than the traditional daily oral administration.
M. Gallieni, D. Brancaccio
core  

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

The interplay between vitamin D status, subclinical inflammation, and prediabetes

Heliyon
Vitamin D's role extends beyond classical calcium and phosphate homeostasis to encompass a pivotal influence on immune modulation and metabolic health.
Ahmed Arabi, Dima Nasrallah, Sara Mohsen, Lana Abugharbieh, Dana Al-Hashimi, Shaikha AlMass, Shahd Albasti, Saeed A. Al-Ajmi, Susu M. Zughaier   +8 more
doaj   +1 more source

Circadian Clock Regulates Epidermal Endocrine System in Homeostatic Skin Pigmentation

Experimental Dermatology, Volume 35, Issue 6, June 2026.
ABSTRACT The circadian clock regulates multiple physiological processes in the skin, including local hormone synthesis and pigmentation. However, how circadian regulation interacts with epidermal endocrine signalling in melanocytes remains unclear.
Anya Zhu, Lingli Yang, Sylvia Lai, Fei Yang, Daisuke Tsuruta, Ichiro Katayama   +5 more
wiley   +1 more source

Pathogenesis of refractory secondary hyperparathyroidism

, 2002
Pathogenesis of refractory secondary hyperparathyroidism. Calcitriol is currently used to reduce parathyroid hormone (PTH) levels in uremic patients. However, a significant number of patients fail to respond to calcitriol therapy. The data suggest that a
Rodriguez, Mariano, Canalejo, Antonio, Garfia, Bartolome, Almaden, Yolanda, Aguilera, Escolastico   +4 more
core   +1 more source

Pathogenesis of secondary hyperparathyroidism

, 1999
Pathogenesis of secondary hyperparathyroidism. Secondary hyperparathyroidism is a universal complication in patients with chronic renal failure. Hyperplasia of the parathyroid glands is typically seen in these patients. In early renal failure, alteration
Slatopolsky, Eduardo, Brown, Alex, Dusso, Adriana   +2 more
core   +1 more source

The role of vitamin D in the prevention and treatment of autoimmune diseases – A literature review and analysis of research

Journal of Education, Health and Sport
Introduction and purpose. Autoimmune diseases are a group of diseases in which the immune system attacks the body's own cells, leading to chronic inflammation and tissue damage. In the pathogenesis of these diseases, dysregulation of the immune response,
Monika Zawół, Mariusz Zimonczyk, Wiktoria Pawlik, Paweł Nojek, Agnieszka Nowotarska, Gustaw Błaszczyński   +5 more
doaj   +1 more source

Effects of calcitriol on phagocytic function, toll-like receptor 4 expression, and cytokine production of canine leukocytes

American Journal of Veterinary Research, 2018
Abstract OBJECTIVE To determine the in vitro effects of calcitriol on indicators of immune system function in blood samples collected from healthy dogs. SAMPLE Blood samples from 8 healthy adult dogs.
Jared A, Jaffey, Juliana, Amorim, Amy E, DeClue   +2 more
openaire   +2 more sources