Elevated Levels of 1,25-Dihydroxyvitamin D in Plasma as a Missing Risk Factor for Celiac Disease
Clinical and Experimental Gastroenterology, 2020 Seth Scott Bittker Ronin Institute, Montclair, NJ, USACorrespondence: Seth Scott Bittker 17 Edmond Street, Darien, CT 06820, USATel +1 212-203-6550Email sbittker@yahoo.comAbstract: The prevalence of celiac disease (CD) has increased significantly in some
Bittker SS
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Molecular pharmacology of AMPA receptor trafficking proteins - TARPs - evidence for an association with 5HT(_2c) receptors [PDF]
, 2009 There has been an increasing awareness of the involvement of neurotransmitters other than serotonin in depression, with new antidepressants possessing effects on other receptor types, such as Agomelatine®, an antagonist of 5HT(_2c) receptors that ...
Donoghue, Peter, Donoghue , Peter
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CYP24A1 Inhibition Enhances the Antitumor Activity of Calcitriol
, 2010 High systemic exposures to calcitriol are necessary for optimal antitumor effects. Human prostate cancer PC3 cells are insensitive to calcitriol treatment.
Kristie L. Engler +6 more
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TREATMENT OPTIONS FOR COVID-19 WITH VITAMIN D SUPPLEMENTS
Клінічна та профілактична медицинаIntroduction. Recently, the study of the relationship between vitamin D deficiency and adequate immune response has been of particular interest, particularly in the context of the COVID-19 pandemic and its impact on disease prognosis.
Tetiana V. Fartushok +2 more
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Purinergic receptors in skeletal muscles in health and in muscular dystrophy [PDF]
, 2014 The P2 purinergic (nucleotide) receptor super-family comprises of two families of protein. The P2X, which are channel-forming ionotropic receptors and the P2Y metabotropic receptors activating G protein-mediated signalling pathways.
Young, Christopher +10 more
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Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity [PDF]
, 2003 A reduction in microglial activation and subsequent neurotoxicity may prove critical for neuroprotection in neurodegenerative diseases. We examined the expression and functionality of group III metabotropic glutamate (mGlu) receptors on microglia.
Taylor, D.L., Pocock, J.M., Diemel, L.T.
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Molecular pharmacological characterisation of recombinant and native NR2B- and NR3B- containing NMDA receptors [PDF]
, 2008 NMDA receptors are ionotropic, glutamate receptors which mediate fast excitatory transmissions within the central nervous system. They form tetrameric or pentameric heterologous complexes from seven NMDA receptor subunits NRl, NR2A-D and NR3A-B which ...
Chaffey, Heather Emily
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Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]
, 2002 GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart +7 more
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This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation ...
Conn, P. Michael.
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Vitamin D3: research breakthroughs and therapeutic use
Annals of Mechnikov's Institute, 2019 Vitamin D3 (cholecalciferol), the natural form of vitamin D, is produced in the skin from 7-dehydrocholesterol. The synthesis of vitamin D in the skin is the most important source of vitamin D.
М Pohorila +6 more
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