Results 11 to 20 of about 56,351 (295)

Cannabinoid receptors [PDF]

Current Biology, 2002
Abstract Cannabinoid receptors are seven transmembrane receptors that mediate the central and peripheral actions of extracts from the cannabis plant. Although many endogenous agonists of cannabinoid receptors have been described, a categorical role of these (mainly fatty acid derived) molecules as the endogenous ligand for cannabinoid ...
D A Kendall, S P H Alexander
  +5 more sources

Some Prospective Alternatives for Treating Pain: The Endocannabinoid System and Its Putative Receptors GPR18 and GPR55

Frontiers in Pharmacology, 2019
Background: Marijuana extracts (cannabinoids) have been used for several millennia for pain treatment. Regarding the site of action, cannabinoids are highly promiscuous molecules, but only two cannabinoid receptors (CB1 and CB2) have been deeply studied ...
Raquel Guerrero-Alba, Paulino Barragán-Iglesias, Abimael González-Hernández, Eduardo E. Valdez-Moráles, Vinicio Granados-Soto, Miguel Condés-Lara, Martín G. Rodríguez, Bruno A. Marichal-Cancino   +7 more
doaj   +1 more source

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects [PDF]

, 2015
Funded by: •GW Pharmaceuticals Acknowledgements: The authors wish to thank Mrs Lesley Stevenson for technical support and Dr John Raymond, Dr Keith Parker and Dr Ethan Russo for providing human 5-HT1A CHO cells.
Cascio, Maria Grazia, Marini, Pietro, Parolaro, Daniela, Pertwee, Roger G., Zamberletti, Erica   +4 more
core   +1 more source

Expression of the endocannabinoid receptors in human fascial tissue

European Journal of Histochemistry, 2016
Cannabinoid receptors have been localized in the central and peripheral nervous system as well as on cells of the immune system, but recent studies on animal tissue gave evidence for the presence of cannabinoid receptors in different types of tissues ...
C. Fede, G. Albertin, L. Petrelli, M.M. Sfriso, C. Biz, R. De Caro, C. Stecco   +6 more
doaj   +1 more source

Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation [PDF]

, 2011
The herb Cannabis sativa (C. sativa) has been used in China and on the Indian subcontinent for thousands of years as a medicine. However, since it was brought to the UK and then the rest of the western world in the late 19th century, its use has been a ...
Adams, Agrawal, Ahern, Alger, Armstrong, Arnone, Avraham, Bachur, Baker, Baker, Barbano, Basavarajappa, Basavarajappa, Ben Amar, Ben-Zvi, Berridge, Berridge, Bisogno, Blankman, Bortolato, Breivogel, Brown, Brown, Burkey, Cadas, Cahn, Chan, Childers, Clark, Comelli, Consroe, Costiniuk, Cota, Cota, Cota, Cravatt, Davis, Davis, De Filippis, De Petrocellis, De Petrocellis, Deadwyler, Dennis, Deutsch, Devane, Devane, Dewey, Di Marzo, Di Marzo, Di Marzo, Di Marzo, Di Marzo, Elmquist, Engeli, Evans, Fadda, Farrimond, Farrimond, Felder, Fong, Fonseca, Fredriksson, Freund, Gaetani, Gallate, Gaoni, Gaoni, Gaoni, Gardner, Gatley, Gerdeman, Gill, Glass, Glick, Gomez, Gong, Goutopoulos, Grant, Hao, Henstridge, Henstridge, Herkenham, Herkenham, Higgs, Hohmann, Holland, Hollister, Horswill, Hosohata, Howlett, Howlett, Howlett, Huffman, Hughes, Ishiguro, Izzo, Jamshidi, Jarrett, Jarrett, Jin, Kapur, King, Kirby, Kirkham, Kirkham, Kirkham, Kirkham, Kirkham, Koch, Lambert, Landsman, Lauckner, Lauckner, Ligresti, Little, Liu, Long, Ma, Maccarrone, Maccarrone, Mackie, Mackie, Makriyannis, Martin, Mathes, Matsuda, Mechoulam, Mechoulam, Moldrich, Morgan, Morley, Munro, Naidu, Ning, Ohno-Shosaku, Okamoto, Okamoto, Okamoto, Onaivi, Onaivi, Onaivi, Osei-Hyiaman, Overton, Overton, Oz, Pacheco, Pertwee, Pertwee, Pertwee, Pertwee, Pertwee, Pertwee, Pertwee, Pertwee, Petitet, Petrosino, Pietr, Piomelli, Piomelli, Piomelli, Pope, Pryce, Pryce, Putney, Rao, Riedel, Rinaldi-Carmona, Rinaldi-Carmona, Rodriguez de Fonseca, Ronesi, Ross, Ross, Ryan, Ryberg, Sanger, Sawzdargo, Schweitzer, Showalter, Simiand, Sink, Sofia, Soga, Solinas, Staton, Stratford, Sugiura, Sugiura, Sugiura, Südhof, Takeda, Thomas, Thornton-Jones, Tramer, Tsou, Turu, Van Gaal, Van Sickle, Vandevoorde, Walsh, Wang, Werner, Whalley, Wiley, Wilkinson, Williams, Williams, Williams, Williams, Williamson, Wilson, Woolridge, Yamauchi, Yan, Yates, Yoshida, Zhu   +215 more
core   +3 more sources

Novel cannabinoid receptors [PDF]

British Journal of Pharmacology, 2007
Cannabinoids have numerous physiological effects. In the years since the molecular identification of the G protein‐coupled receptors CB1 and CB2, the ion channel TRPV1, and their corresponding endogenous ligand systems, many cannabinoid‐evoked actions have been shown conclusively to be mediated by one of these specific receptor targets.
openaire   +2 more sources

Role of Cannabinoid Receptors in Psychological Disorder

Borneo Journal of Pharmacy, 2020
Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system. Cannabinoid CB1 and CB2 receptors are G protein-coupled receptors present from the early stages of gestation, which is involved in various physiological processes,
Ambika Nand Jha, Dhaval M Patel
doaj   +1 more source

Distribution of Cannabinoid Receptors in Keratinocytes of Healthy Dogs and Dogs With Atopic Dermatitis

Frontiers in Veterinary Science, 2022
It is commonly accepted that some form of skin barrier dysfunction is present in canine atopic dermatitis (AD), one of the most common cutaneous pruritic inflammatory diseases of dogs.
Roberto Chiocchetti, Margherita De Silva, Francesca Aspidi, Rodrigo Zamith Cunha, Francesca Gobbo, Claudio Tagliavia, Giuseppe Sarli, Maria Morini   +7 more
doaj   +1 more source

Functional role of cannabinoid receptors in urinary bladder

Indian Journal of Urology, 2010
Cannabinoids, the active components of Cannabis sativa (marijuana), and their derivatives produce a wide spectrum of central and peripheral effects, some of which may have clinical applications.
Pradeep Tyagi, Vikas Tyagi, Naoki Yoshimura, Michael Chancellor   +3 more
doaj   +1 more source

Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner [PDF]

, 2016
Cannabinoid receptor interacting protein 1a (CRIP1a) is a CB1 receptor (CB1R) distal C-terminus-associated protein that modulates CB1R signaling via G proteins, and CB1R down-regulation but not desensitization (Blume et al.
Bass, Caroline E., Blumes, Lawrence C, Chen, Rong, Howlett, Allyn C., Leone-Kabler, Sandra, Luessen, Deborah J., Lyons, Erica, Marrs, Glenn S., Selley, Dana E.   +8 more
core   +2 more sources