Results 91 to 100 of about 2,926,869 (253)

The melanocortin receptors and their accessory proteins. [PDF]

, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF, Clark, AJ, Gorrigan, RJ, Ramachandrappa, S   +3 more
core   +2 more sources

Endothelial Cell Inflammation and Barriers Are Regulated by the Rab26-Mediated Balance between β2-AR and TLR4 in Pulmonary Microvessel Endothelial Cells

Mediators of Inflammation, 2019
Rab26 GTPase modulates the trafficking of cell surface receptors, such as G protein-coupled receptors including α2-adrenergic receptors in some cell types.
Huaping Chen, Ming Yuan, Chunji Huang, Zhi Xu, Mingchun Li, Chun Zhang, Zhan Gao, Mingzhou Zhang, Jiancheng Xu, Hang Qian, Jiegen You, Binfeng He, Guansong Wang, Mingdong Hu   +13 more
doaj   +1 more source

Modelling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion [PDF]

, 2016
We have developed a mathematical framework for describing a bispecific monoclonal antibody interaction with two independent membrane-bound targets that are expressed on the same cell surface.
Argungu, Maryam, Hadji, Aymen, Hawkins, Emma, McGinty, Sean, Nouri, Fatma Z., Sengers, Bram G., Sepp, Armin, Taylor, Adam, Weber, Andrew   +8 more
core   +1 more source

Mobility of cell surface receptors: a re‐evaluation

FEBS Letters, 1998
It has long been known from fluorescence recovery after photobleaching experiments that the mobility of most cell surface receptors is much smaller than expected for free diffusion of proteins in a fluid lipid bilayer. Single‐particle tracking experiments are currently revealing the complexity of the constraints to free diffusion.
Patricia R. Smith, Ian E. G. Morrison, Richard J. Cherry, Nelson Fernandez   +3 more
openaire   +3 more sources

Analyzing the Role of Receptor Internalization in the Regulation of Melanin-Concentrating Hormone Signaling

International Journal of Endocrinology, 2013
The regulation of appetite is complex, though our understanding of the process is improving. The potential role for the melanin-concentrating hormone (MCH) signaling pathway in the treatment of obesity is being explored by many.
Jay I. Moden, Katrina Haude, Robert Carroll, Andrew Goodspeed, Laurie B. Cook   +4 more
doaj   +1 more source

A natural killer cell receptor specific for a major histocompatibility complex class I molecule. [PDF]

, 1994
Target cell expression of major histocompatibility complex (MHC) class I molecules correlates with resistance to lysis by natural killer (NK) cells.
Daniels, BF, Karlhofer, FM, Seaman, WE, Yokoyama, WM   +3 more
core  

Non-classical immunology. Meeting Report [PDF]

, 2001
This large annual immunology meeting covered a wide range of subjects from biochemical protein characterizations to cell biology and the study of complex disease pathologies.
Allen, RL
core   +1 more source

NKp44 and Natural Cytotoxicity Receptors as Damage Associated Molecular Pattern Recognition Receptors

Frontiers in Immunology, 2015
Natural Killer (NK) cells are a key constituent of the innate immune system, protecting against bacteria, virally infected cells, and cancer. Recognition and protective function against such cells is dictated by activating and inhibitory receptors on ...
Porunelloor Abraham Mathew, Nathan Chad Horton   +1 more
doaj   +1 more source

Innate Immunity and Cell Surface Receptors in the Pathogenesis of COPD: Insights from Mouse Smoking Models

International Journal of COPD, 2020
Giovanna De Cunto, Eleonora Cavarra, Barbara Bartalesi, Monica Lucattelli, Giuseppe Lungarella Department of Molecular and Developmental Medicine, University of Siena, Siena, ItalyCorrespondence: Giuseppe Lungarella Email lungarella.giuseppe@gmail ...
De Cunto G, Cavarra E, Bartalesi B, Lucattelli M, Lungarella G   +4 more
doaj  

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. [PDF]

, 1991
We investigated the role of the integrins alpha v beta 3 and alpha v beta 5 in mediating vitronectin adhesion of three phenotypically distinct cell types.
Cheresh, DA, Orlando, RA, Wayner, EA
core