Results 91 to 100 of about 1,161,650 (208)

Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration

Nature Communications, 2017
Integrin αβ heterodimer cell surface receptors mediate adhesive interactions that provide traction for cell migration. Here the authors show that actin flow can orient cell surface integrins during leukocyte migration, suggesting integrin activation by ...
Pontus Nordenfelt, Travis I. Moore, Shalin B. Mehta, Joseph Mathew Kalappurakkal, Vinay Swaminathan, Nobuyasu Koga, Talley J. Lambert, David Baker, Jennifer C. Waters, Rudolf Oldenbourg, Tomomi Tani, Satyajit Mayor, Clare M. Waterman, Timothy A. Springer   +13 more
doaj   +1 more source

Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. [PDF]

, 2019
Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of β1 adrenergic receptors (βARs) on cardiac myocytes.
Irannejad, Roshanak, Nash, Craig A, Smrcka, Alan V, Wei, Wenhui   +3 more
core   +1 more source

Effects of acute exercise on expressions of functional receptors on CD56dim and CD56bright natural killer cells [PDF]

, 2014
PURPOSE: Mobilization and cytotoxicity of natural killer (NK) cells are regulated by cell surface receptors such as adhesion molecules and activating/inhibitory receptors.
Okumura, Ko, Shek, Pang N, Shephard, Roy J, Suzui, Masatoshi, Takeda, Kazuyoshi, Yagita, Hideo   +5 more
core   +1 more source

Cis - trans interactions of cell surface receptors: biological roles and structural basis [PDF]

, 2018
Cell surface receptors bind ligands expressed on other cells (in trans) in order to communicate with neighboring cells. However, an increasing number of cell surface receptors are found to also interact with ligands expressed on the same cell (in cis ...
Held, Werner, Mariuzza, Roy
core  

Ligand-Receptor Interactions

, 2008
The formation and dissociation of specific noncovalent interactions between a variety of macromolecules play a crucial role in the function of biological systems.
Alder B J, Alon R, Amit A G, André P, Antosiewicz J, Ashkin A, Atherton A, Atherton A, Balsera M, Beeson C, Bell G I, Bell G I, Berg H C, Berg H C, Bhat T N, Boland T, Bongrand P, Bongrand P, Brady G P, Brooks B R, Brune D, Brunk D K, Böhm H J, Böhm H J, Cantor C R, Capo C, Chesla S E, Chilkoti A, Choquet D, Chu L, Clackson T, Claesson P M, Collins F C, Connelly P R, Creighton T E, Creighton T E, Curtis A S G, Danmer U, Danmer U, Debye P, deLisi C, Dembo M, Dustin M L, Eisenberg D, Eisenberg D, Erlandsson R, Ermak D L, Evans E, Evans E, Evans E A, Evans E A, Evans E A, Evans E A, Evans E A, Eyring H, Eyring H, Fersht A, Florin E L, Gabdouline R R, Garboczi D N, Gilson M K, Goldsmith H L, Grubmüller H, Grutter M G, Hammer D A, Hammer D A, Helm C, Hill T L, Hirschefelder J O, Hoh J H, Honig B, Israelachvili J N, Israelachvili J N, Israelachvili J N, Izrailev S, Jencks W P, Jorgensen W L, Jorgensen W L, Kabat E A, Kaplanski G, Karplus M, Kishino A, Kozack R E, Kramers H A, Kuo S C, Kupfer A, Kwong D, Lawrence M B, Lawrence M B, Leckband D E, Leckband D E, Lee B, Lee C Y, Lee G U, Liebert R B, Lollo B A, London F, Maitland G C, Margenau H, Marston S B, Martorana V, McClay D R, McCloskey M A, Merkel R, Metropolis M, Meyhöfer E, Miyamoto S, Moy V T, Nishizaka T, Northrup S H, Northrup S H, Ooi T, Page M J, Palecek S P, Pangali C, Patel K D, Pauling L, Pierres A, Pierres A, Pierres A, Piper J W, Pratt L R, Richards F F, Richards F M, Rossky P J, Sato M, Schmid-Schöenbein G W, Schoup D, Schreiber G, Schuster P, Schwartz L, Smith S B, Sommerfeld A, Sommerfeld A, Steward M W, Stone S R, Stossel T P, Strick T R, Sturtevant J M, Szabo A, Szabo A, Szczesniak M M, Tees D F, Tha S P, Tsao Y H, Tulip W R, Vajda S, Valentine R C, van der Merwe P A, Vinckier A, von Andrian U H, von Fuchs, von Smoluchowski M, Voss Jr E W, Weast R C, Weber P C, Williams A-F, Winter C C, Wurmser R, Zurkhov S N   +159 more
core   +1 more source

Synthetic transmembrane DNA receptors enable engineered sensing and actuation

Nature Communications
In living organisms, cells synergistically couple cascade reaction pathways to achieve inter- and intracellular signal transduction by transmembrane protein receptors.
Ze-Rui Zhou, Man-Sha Wu, Zhenglin Yang, Yuting Wu, Weijie Guo, Da-Wei Li, Ruo-Can Qian, Yi Lu   +7 more
doaj   +1 more source

Cell surface patching via CXCR4-targeted nanothreads for cancer metastasis inhibition

Nature Communications
The binding of therapeutic antagonists to their receptors often fail to translate into adequate manipulation of downstream pathways. To fix this ‘bug’, here we report a strategy that stitches cell surface ‘patches’ to promote receptor clustering, thereby
Minglu Zhou, Chendong Liu, Bo Li, Junlin Li, Ping Zhang, Yuan Huang, Lian Li   +6 more
doaj   +1 more source

Cell Surface Receptor [PDF]

, 2020
openaire   +1 more source

Plant cell surface receptors. [PDF]

Plant J
Ngou BPM, Kadota Y, Shirasu K.
europepmc   +1 more source

Insights into ectodomain shedding as a novel target in natural killer cell-based immunotherapy for cancer. [PDF]

Front Immunol
Pimenta R, Arai J, Ribeiro de Lima Brandao L, Schmidt P, da Silva Bortoleti BT, Ferrari de Andrade L.   +5 more
europepmc   +1 more source