Results 11 to 20 of about 2,926,869 (253)

Cell surface receptors for CCN proteins [PDF]

open access: yesJournal of Cell Communication and Signaling, 2016
The CCN family (CYR61; CTGF; NOV; CCN1-6; WISP1-3) of matricellular proteins in mammals is comprised of six homologous members that play important roles in development, inflammation, tissue repair, and a broad range of pathological processes including fibrosis and cancer.
L. Lau
openaire   +4 more sources

Interaction of KSHV with Host Cell Surface Receptors and Cell Entry

open access: yesViruses, 2014
Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil   +3 more
doaj   +2 more sources

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly [PDF]

open access: yes, 2010
Erythropoetin-producing hepatoma (Eph) receptors are cell-surface protein tyrosine kinases mediating cell-cell communication. Upon activation, they form signaling clusters.
A Radu Aricescu   +57 more
core   +1 more source

Aptamers for Targeted Drug Delivery

open access: yesPharmaceuticals, 2010
Aptamers are a class of therapeutic oligonucleotides that form specific three-dimensional structures that are dictated by their sequences. They are typically generated by an iterative screening process of complex nucleic acid libraries employing a ...
Partha Ray, Rebekah R. White
doaj   +1 more source

The role of cellular adhesion molecules in virus attachment and entry [PDF]

open access: yes, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source

Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. [PDF]

open access: yes, 2010
DNAX adaptor protein 12 (DAP12) is a trans-membrane adaptor molecule that transduces activating signals in NK and myeloid cells. Absence of functional Dap12 results in osteoclast defects and bone abnormalities.
Adamopoulos, Iannis E   +11 more
core   +3 more sources

Cell-surface receptors enable perception of extracellular cytokinins

open access: yesNature Communications, 2020
The main site of cytokinin perception in plant cells is thought to be the endoplasmic reticulum where most cytokinin receptors localise. Here via the use of bioactive probes that cannot enter plant cells and super-resolution microscopy, Antoniadi et al ...
Ioanna Antoniadi   +18 more
doaj   +1 more source

Research Progress of Dendritic Cell Surface Receptors and Targeting

open access: yesBiomedicines, 2023
Dendritic cells are the only antigen-presenting cells capable of activating naive T cells in humans and mammals and are the most effective antigen-presenting cells.
Chunyu Tong   +6 more
doaj   +1 more source

Activation of transmembrane cell‐surface receptors via a common mechanism? The “rotation model”

open access: yesBioessays, 2015
It has long been thought that transmembrane cell‐surface receptors, such as receptor tyrosine kinases and cytokine receptors, among others, are activated by ligand binding through ligand‐induced dimerization of the receptors.
I. Maruyama
semanticscholar   +1 more source

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