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Initial Step of Virus Entry: Virion Binding to Cell-Surface Glycans.
Annual Review of Virology, 2020Virus infection is an intricate process that requires the concerted action of both viral and host cell components. Entry of viruses into cells is initiated by interactions between viral proteins and cell-surface receptors.
M. Koehler +4 more
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Cell surface adhesion receptors
Current Opinion in Structural Biology, 1994Several new structural motifs found in cell surface adhesion receptors have been described in the past few years. Also, several two-domain structures of extracellular portions of cell surface proteins have been reported. Structural models for complexes between receptors and counter-receptors have been proposed.
Gerhard Wagner, Daniel F. Wyss
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Emerging Applications of Nanotechnology for Controlling Cell-Surface Receptor Clustering.
Angewandte Chemie, 2019The spatial organization of cell-surface receptors plays an important role in defining cell fate. Recently, the development of strategies for the direct regulation of receptor clustering using nanomaterials has aroused enormous interest.
Kaixiang Zhang +3 more
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Cell Surface Receptors for Gammaretroviruses
2003Evidence obtained during the last few years has greatly extended our understanding of the cell surface receptors that mediate infections of retroviruses and has provided many surprising insights. In contrast to other cell surface components such as lectins or proteoglycans that influence infections indirectly by enhancing virus adsorption onto specific
Mariana Marin +3 more
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Cytokine receptor activation at the cell surface
Current Opinion in Structural Biology, 2012Cytokines are well recognized for the pleiotropic nature of their signaling and biological activities on many cell types and their role in health and disease. Recent years have seen a steady stream of new cytokine receptor crystal structures including those that are activated by GM-CSF, type I interferon, and a variety of interleukins.
Sophie E. Broughton +4 more
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Cell surface receptors in lysophospholipid signaling [PDF]
Seminars in Cell & Developmental Biology, 2004 The lysophospholipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), regulate various signaling pathways within cells by binding to multiple G protein-coupled receptors. Receptor-mediated LPA and S1P signaling induces diverse cellular responses including proliferation, adhesion, migration, morphogenesis, differentiation and survival ...
Jerold Chun, Brigitte Anliker
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A model of cell surface receptor aggregation
Journal of Mathematical Biology, 2017In this paper we construct and analyze a model of cell receptor aggregation. Experiments have shown that receptors in an aggregated state have greatly reduced mobility. We model the effects of this reduced mobility with a density dependent diffusion and study the impact of density dependent diffusion on aggregate formation in a one-dimensional domain ...
D. Iron, J. Rumsey
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Cell surface receptors for picornaviruses
BioEssays, 1986AbstractPicornaviruses can be divided into at least six receptor families based on results of competition binding and receptor antibody studies. It has been proposed that a canyon present within the virion capsid harbors the viral attachment site for this group of viruses. Cell surface proteins involved in viral attachment have been identified for both
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