Results 261 to 270 of about 2,880,433 (308)
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Targeting of Drugs to Cell Surface Receptors
Critical Reviews in Biotechnology, 1997The new approach to the treatment of cancer or to immunomodulation is drug targeting. The effort to achieve either an absolute or a relative amplification of the tumoricidal effect of anticancer drugs through increased generation or acquisition of reactive molecules at the tumor site or a reduction of the toxic molecules available to the periphery has ...
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Surface NK receptors and their ligands on tumor cells
Seminars in Immunology, 2006The identification of MHC-class I-specific inhibitory receptors in humans and mice provided a first explanation of why NK cells can kill target cells that have lost or underexpress MHC-class I molecules but spare normal cells. However, the molecular basis of NK-mediated recognition and tumor cell killing revealed a higher degree of complexity.
MORETTA, ALESSANDRO +5 more
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Mesenchymal Stem Cells and Their Cell Surface Receptors
Current Rheumatology Reviews, 2008Daily increasing evidence indicates that stem cells can be found in nearly every tissue. Mesenchymal stem cells (MSCs) are adult stem cells, which reside in the bone marrow and other mesenchymal tissues. MSCs can be expanded to large numbers and can be driven into diverse mesenchymal cell lineages, including chondrocytes. Therefore, MSCs have attracted
Matthias Schieker +2 more
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Cell surface immunoglobulin receptors in B cell development
Seminars in Immunology, 2002Expression of surface immunoglobulin (sIg) related receptors has been conserved in phylogenetically distinct species as a critical checkpoint in B cell development. The sIg receptor comprises extracellular IgM heavy and light chains, with the potential for ligand binding, complexed to the Igalpha/Igbeta heterodimer that is responsible for signal ...
Michael J.H. Ratcliffe +2 more
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The Anchorage of Cell Surface Receptors to the Cytoskeleton [PDF]
, 1981 It is now accepted that the cytoplasm of most cells is not a simple fluid but rather a complex gel, the structure of which is maintained by a variety of intracellular filaments, notably the microfilaments, microtubules and intermediate filaments, collectively referred to as the cytoskeleton.
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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
Nature, 1987Jie Kang +8 more
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Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
Nature Biotechnology, 2005Erwei Song +11 more
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Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021, Kenar D Jhaveri, Mark A Perazella
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