Results 71 to 80 of about 1,161,650 (208)

Robust formation of morphogen gradients

open access: yes, 2004
We discuss the formation of graded morphogen profiles in a cell layer by nonlinear transport phenomena, important for patterning developing organisms. We focus on a process termed transcytosis, where morphogen transport results from binding of ligands to
A. Eldar   +12 more
core   +1 more source

SARM1 is essential for NMDA receptor-dependent endocytosis of AMPA receptors in hippocampal neurons

open access: yesNeuroscience Research
Long-term depression (LTD) is a form of synaptic plasticity thought to be the cellular basis of experience-dependent learning and memory. LTD is caused by an activity-dependent decrease in cell surface α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Misaki Morishita, Shinji Matsuda
doaj   +1 more source

The Cell Density Factor CMF Regulates the Chemoattractant Receptor cAR1 in Dictyostelium [PDF]

open access: yes, 1996
Starving Dictyostelium cells aggregate by chemotaxis to cAMP when a secreted protein called conditioned medium factor (CMF) reaches a threshold concentration.
Bishop, John D.,   +2 more
core   +4 more sources

Sugar Free: Novel Immunotherapeutic Approaches Targeting Siglecs and Sialic Acids to Enhance Natural Killer Cell Cytotoxicity Against Cancer

open access: yesFrontiers in Immunology, 2019
Natural Killer (NK) cells are cytotoxic lymphocytes that play a key role in the immune system, targeting and destroying invading pathogens and malignantly transformed cells.
John Daly   +2 more
doaj   +1 more source

Distinct agonist regulation of muscarinic acetylcholine M2-M3 heteromers and their corresponding homomers [PDF]

open access: yes, 2015
Each subtype of the muscarinic receptor family of G protein-coupled receptors is activated by similar concentrations of the neurotransmitter acetylcholine or closely related synthetic analogs such as carbachol. However, pharmacological selectivity can be
Alvarez-Curto, Elisa   +3 more
core   +1 more source

Guanylate Cyclase, a Cell Surface Receptor

open access: yesJournal of Biological Chemistry, 1989
Guanylate cyclase appears to represent a central member of a diverse family of proteins involved in cell signaling mechanisms including the protein kinases, a low Mr ANP receptor, and possibly adenylate cyclase (based on limited sequence identity with the yeast enzyme).
openaire   +2 more sources

Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth. [PDF]

open access: yes, 1987
Neuronal responses to extracellular matrix (ECM) constituents are likely to play an important role in nervous system development and regeneration. We have studied the interactions of a neuron-like rat pheochromocytoma cell line, PC12, with ECM protein ...
Damsky, CH, Reichardt, LF, Tomaselli, KJ
core  

Nanoparticles-cell association predicted by protein corona fingerprints [PDF]

open access: yes, 2016
In a physiological environment (e.g., blood and interstitial fluids) nanoparticles (NPs) will bind proteins shaping a "protein corona" layer. The long-lived protein layer tightly bound to the NP surface is referred to as the hard corona (HC) and encodes ...
Caracciolo, Giulio   +6 more
core   +1 more source

The melanocortin receptors and their accessory proteins. [PDF]

open access: yes, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF   +3 more
core   +2 more sources

Endothelial Cell Inflammation and Barriers Are Regulated by the Rab26-Mediated Balance between β2-AR and TLR4 in Pulmonary Microvessel Endothelial Cells

open access: yesMediators of Inflammation, 2019
Rab26 GTPase modulates the trafficking of cell surface receptors, such as G protein-coupled receptors including α2-adrenergic receptors in some cell types.
Huaping Chen   +13 more
doaj   +1 more source

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