Results 241 to 250 of about 275,691 (287)

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Harnessing the Power of CAR-NK Cells for Solid Tumors: Challenges, Innovations, and Future Frontiers in Immunotherapy. [PDF]

Cancer Commun (Lond)
An M, Yan J, Liu B, Liu Q.
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Tumor-associated neutrophils in pancreatic ductal adenocarcinoma: mechanisms and therapeutic targeting. [PDF]

Front Immunol
Wu X, Zhu W, Chen W, Ruan L.
europepmc   +1 more source

Macrophage-derived chemokines in T cell regulation: implications for cancer immunotherapy. [PDF]

Front Immunol
Zhang K, Liu J, Liu Q, Zhu N, Ye B.
europepmc   +1 more source

The Role of Rarely Studied Chemokines in Tumor Progression in Multiple Myeloma (MM). [PDF]

Cancers (Basel)
Korbecki J, Bosiacki M, Stelmach R, Barczak K.   +3 more
europepmc   +1 more source

A CD25-chemokine receptor complex initiates noncanonical IL-2 signaling. [PDF]

J Biol Chem
Lee HS, Kim SHJ, Aceil J, Meecham A, Gingras A, Ley K, Spangler JB, Ginsberg MH.   +7 more
europepmc   +1 more source

Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation. [PDF]

PLoS One
Danis J, Kelemen E, Balogh F, Szabó K, Fodor GH, Ádám É, Széll M.   +6 more
europepmc   +1 more source

Microglia, Astrocytes, and Oligodendrocytes in Parkinson's Disease: Neuroinflammatory Crosstalk and Emerging Therapeutic Strategies. [PDF]

Biomolecules
Kędzia D, Galita G, Majsterek I, Rozpędek-Kamińska W.   +3 more
europepmc   +1 more source