Results 81 to 90 of about 30,055 (235)

How Different Traditional and Modern Coffee Brewing Methods Affect Its Aroma, Chemistry, Health Effects and Safety Attributes?—A Comprehensive Review to Maximize Coffee Brew Quality

open access: yeseFood, Volume 7, Issue 2, April 2026.
This review article provides a comprehensive analysis of coffee pre‐brewing techniques, focusing on the methodology and key parameters involved in each coffee brewing process. It also summarizes how different brewing methods affect the coffee metabolome, antioxidant levels, aroma, and physicochemical features.
Enas A. El‐Hawary   +5 more
wiley   +1 more source

High expression of peptide receptors as a novel target in gastrointestinal stromal tumours [PDF]

open access: yes, 2018
Recent significant advances in understanding the biology of gastrointestinal stromal tumours (GIST) have led to the introduction of a new targeted therapy (imatinib mesylate, Glivec).
Guillou, Louis   +4 more
core  

From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]

open access: yes, 2016
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni   +3 more
core   +2 more sources

Feeding Behaviour in the KPC Model of Pancreatic Cancer‐Associated Cachexia: Alteration of Spontaneous and Evoked Feeding Behaviours

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background The KPC mouse model of pancreatic cancer is gaining use in research, but detailed understanding of ingestive behaviour changes in this and other cachexia models is limited. Methods Male C57BL/6 J mice (7 weeks) were maintained under standard feed (PicoLab5L0D) and housing conditions (12:12 h; Light:Dark).
Fateema Muzaffar   +2 more
wiley   +1 more source

Vagal Blocking for Obesity Control : a Possible Mechanism-Of-Action [PDF]

open access: yes, 2016
14 September 2016 Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action Helene Johannessen, David Revesz, Yosuke Kodama, Nikki Cassie, Karolina P Skibicka, Perry Barrett, Suzanne Dickson, Jens Holst, Jens Rehfeld, Geoffrey van ...
Adan, Roger   +14 more
core   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

New Insights in the Design of Bioactive Peptides and Chelating Agents for Imaging and Therapy in Oncology

open access: yesMolecules, 2017
Many synthetic peptides have been developed for diagnosis and therapy of human cancers based on their ability to target specific receptors on cancer cell surface or to penetrate the cell membrane.
Anna Lucia Tornesello   +3 more
doaj   +1 more source

Long‐term risk of acute pancreatitis in patients with celiac disease: A nationwide population‐based cohort study

open access: yesJournal of Internal Medicine, Volume 299, Issue 4, Page 515-528, April 2026.
Abstract Background Large‐scale studies on the association between celiac disease (CeD) and acute pancreatitis (AP) are scarce. Objectives To investigate the long‐term risks of incident and recurrent AP in patients with CeD. Methods Through the Swedish nationwide histopathology cohort Epidemiology Strengthened by Histopathology Reports in Sweden, we ...
Jialu Yao   +10 more
wiley   +1 more source

Paraventricular hypothalamic input to anterior cingulate cortex controls food preferences in chronic visceral pain mice

open access: yesNature Communications
Chronic visceral pain is frequently accompanied by changes in food preference. The paraventricular hypothalamus (PVH) and the anterior cingulate cortex (ACC) are well-known regions involved in pain processing and food intake.
Qi-Ya Xu   +9 more
doaj   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 1733-1745, 1 April 2026.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh   +6 more
wiley   +1 more source

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