Results 101 to 110 of about 30,225 (238)

Neuroendocrine control of satiation [PDF]

open access: yes, 2017
Eating is a simple behavior with complex functions. The unconscious neuroendocrine process that stops eating and brings a meal to its end is called satiation. Energy homeostasis is mediated accomplished through the control of meal size via satiation.
Asarian, Lori, Bächler, Thomas
core  

Dialectics of perisomatic inhibition—The unity and conflict of opposites

open access: yesFrontiers in Neural Circuits
Over the past three decades, a great deal of attention has been paid to the study of perisomatic inhibition and perisomatic inhibitory basket cells. A growing body of experimental evidence points to the leading role of perisomatic inhibitory cells in the
Andrei Rozov   +9 more
doaj   +1 more source

In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging [PDF]

open access: yes, 2004
Regulatory peptides and their analogs are being extensively investigated as radiopharmaceuticals for cancer imaging and therapy. Receptors of the cholecystokinin family have been shown to be overexpressed in different types of neuroendocrine tumors ...
A. Zannetti   +10 more
core  

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.

open access: yesPLoS Biology
Development of optimal therapeutics for disease states that can be associated with increased membrane cholesterol requires better molecular understanding of lipid modulation of the drug target.
Kaleeckal G Harikumar   +13 more
doaj   +1 more source

Ultrastructural evidence of a secretory role for melatonin in the human parotid gland [PDF]

open access: yes, 2015
In vivo animal studies show that pentagastrin, cholecystokinin and melatonin cause the secretion and synthesis of salivary proteins. Melatonin occurs in large amounts in the gut and is released into the blood on food intake.
Ekstrom, J.   +6 more
core  

Microbiome affects mice metabolic homeostasis via differential regulation of gene expression in the brain and gut

open access: yesPhysiological Reports
The gut microbiome (GMB) regulates digestion, metabolism, immunity, and energy homeostasis. This study investigates how gut microbiota integrate the regulation in the neuroendocrine and enteroendocrine systems, with a focus on G protein‐coupled receptors
Wynne Milhouse   +6 more
doaj   +1 more source

Relevance of somatostatin receptors and other peptide receptors in pathology [PDF]

open access: yes, 2018
Receptors for regulatory peptides can be overexpressed by several diseases, in particular by neoplasms. This review summarizes the current status of knowledge in this field, on the basis of in vitro receptor studies and with emphasis on receptors for ...
Reubi, Jean
core  

Control of energy homeostasis by amylin [PDF]

open access: yes, 2018
Amylin is an important control of nutrient fluxes because it reduces energy intake, modulates nutrient utilization by inhibiting postprandial glucagon secretion, and increases energy disposal by preventing compensatory decreases of energy expenditure in ...
Lutz, Thomas
core  

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