Results 111 to 120 of about 437,706 (248)

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

The Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet, Johannes Burtscher, Hannes Gatterer, Katharina Hüfner, Samuel Verges, Tadej Debevec, Martin Burtscher   +6 more
wiley   +1 more source

Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs

International Journal of Nanomedicine, 2014
Antonella Accardo,1 Luigi Aloj,2 Michela Aurilio,2 Giancarlo Morelli,1 Diego Tesauro11Centro interuniversitario di Ricerca sui Peptidi Bioattivi (CIRPeB), Department of Pharmacy and Istituto di Biostrutture e Bioimmagini - Consiglio Nazionale delle ...
Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D   +4 more
doaj  

IL‐22Rα1 restrains pancreatic injury independently of its C‐terminal STAT3‐amplifying domain

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
IL‐22R, and to a lesser extent IL‐22, are key drivers of protection in acute pancreatitis. Although the C‐terminal domain of IL‐22R enhances STAT3 activation in the pancreas, it is not required for disease protection. Classical IL‐22R signaling alone is sufficient to control inflammation and promote pancreatic recovery.
Léna Puigdevall, Clara Stewardson, Lysa Dhulst, Emilie Hendrickx, Laure Dumoutier   +4 more
wiley   +1 more source

Expression of the Transcription Factor Egr-1 in Pancreatic Acinar Cells Following Stimulation of Cholecystokinin or Gαq-Coupled Designer Receptors

Cellular Physiology and Biochemistry, 2014
Backgound/Aims: The injection of cerulein, an analogue of the pancreatic secretagogue cholecystokinin (CCK), induces acute pancreatitis in mice that is accompanied by the synthesis of the transcription factor Egr-1.
Anke Kaufmann, Oliver G. Rössler, Gerald Thiel   +2 more
doaj   +1 more source

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu, Xingdong Zeng, Yongle Cai, Haonan Chen, Qianying Li, Hao Yang   +5 more
wiley   +1 more source

Immunolocalization of cholecystokinin-2 receptors in rat gastric mucosa [PDF]

, 2002
Background: Gastrin exerts trophic effects on the gastric mucosa by mechanisms not yet completely elucidated. Our aim was to localize the cholecystokinin-2 (CCK2) receptor in epithelial cells of foetal and adult rat stomachs in order to determine the ...
Borch, K, Borch, Kurt,, Cabero, José Lius,, Hammer, P, Hammer, Pål,, Sundler, Frank,, Mårdh, Sven,, Mardh, S, Sundler, Frank, Tommeras, K, Tømmerås, Karin,, Cabero, JL, Lund University.   +12 more
core   +1 more source

Activation of neural cholecystokinin-1 receptors induces relaxation of the isolated rat duodenum which is reduced by nitric oxide synthase inhibitors

Brazilian Journal of Medical and Biological Research, 2006
Cholecystokinin (CCK) influences gastrointestinal motility, by acting on central and peripheral receptors. The aim of the present study was to determine whether CCK has any effect on isolated duodenum longitudinal muscle activity and to characterize the ...
S.R. Martins, R.B. de Oliveira, G. Ballejo   +2 more
doaj   +1 more source

The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review

Hippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT Hippocampal abnormalities are frequently associated with neurodevelopmental disorders as interneurons are crucial in establishing the network connectivity of neurons. This systematic review analyzed primary literature with a focus on aberrant hippocampal interneuron migration as an etiology for neurodevelopmental disorders, summarizing the ...
M. A. C. Till, H. M. O. Reid, I. Murphy, B. R. Christie   +3 more
wiley   +1 more source

From Guidelines to Clinical Practice: Expert Perspectives on Long‐Term Management of Obesity

Obesity, Volume 34, Issue 9, Page 1708-1717, September 2026.
ABSTRACT An international panel of experts from the U.S. and China convened to discuss the 2026 TOS–OMA–OAC Expert Guidance Statement on the Pharmacological Management of Obesity, focusing on emerging evidence, regional considerations, and challenges in translating recommendations into long‐term care.
Hong Chen, Ling Li, Junqing Zhang, Shaihong Zhu, Marc‐André Cornier, Jonathan Q Purnell   +5 more
wiley   +1 more source

Localization of cholecystokinin mRNA to rat lingual epithelium using in situ hybridization [PDF]

, 1997
Taste buds are spindle-shaped collections of taste receptor cells located in the surface epithelium of the oral cavity. Taste receptor cells are specialized sensory epithelial cells that are responsible for the transmission of taste information to the ...
Lamar, Tiffanie R.
core