Results 81 to 90 of about 16,141 (203)

Activation of neural cholecystokinin-1 receptors induces relaxation of the isolated rat duodenum which is reduced by nitric oxide synthase inhibitors

Brazilian Journal of Medical and Biological Research, 2006
Cholecystokinin (CCK) influences gastrointestinal motility, by acting on central and peripheral receptors. The aim of the present study was to determine whether CCK has any effect on isolated duodenum longitudinal muscle activity and to characterize the ...
S.R. Martins, R.B. de Oliveira, G. Ballejo   +2 more
doaj   +1 more source

Peptide receptors in neuroendocrine tumors of the lung as potential tools for radionuclide diagnosis and therapy

, 2006
Neuroendocrine tumors of the lung are carcinomas characterized by different impact on the patients' prognosis, ranging from relatively indolent, low- to intermediate-grade neoplasms with longer life expectation (i.e., typical and atypical carcinoids) to ...
M. Masullo, G. VIALE, M. Papotti, M. Volante, G. Pelosi, A. Sonzogni   +5 more
core  

Female mice lacking cholecystokinin 1 receptors have compromised neurogenesis, and fewer dopaminergic cells in the olfactory bulb

Frontiers in Cellular Neuroscience, 2013
Neurogenesis in the adult rodent brain is largely restricted to the subependymal zone (SVZ) of the lateral ventricle and subgranular zone (SGZ) of the dentate gyrus (DG).
Yi eSui, Yi eSui, Rob eVermeulen, Rob eVermeulen, Tomas eHökfelt, Malcolm Kenneth Horne, Malcolm Kenneth Horne, Malcolm Kenneth Horne, Davor eStanic, Davor eStanic, Davor eStanic   +10 more
doaj   +1 more source

Dialectics of perisomatic inhibition—The unity and conflict of opposites

Frontiers in Neural Circuits
Over the past three decades, a great deal of attention has been paid to the study of perisomatic inhibition and perisomatic inhibitory basket cells. A growing body of experimental evidence points to the leading role of perisomatic inhibitory cells in the
Andrei Rozov, Andrei Rozov, Andrei Rozov, David John Jappy, David John Jappy, Ksenia Maltseva, Alina Vazetdinova, Alina Vazetdinova, Fliza Valiullina-Rakhmatullina, Fliza Valiullina-Rakhmatullina   +9 more
doaj   +1 more source

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.

PLoS Biology
Development of optimal therapeutics for disease states that can be associated with increased membrane cholesterol requires better molecular understanding of lipid modulation of the drug target.
Kaleeckal G Harikumar, Peishen Zhao, Brian P Cary, Xiaomeng Xu, Aditya J Desai, Maoqing Dong, Jesse I Mobbs, Chirine Toufaily, Sebastian G B Furness, Arthur Christopoulos, Matthew J Belousoff, Denise Wootten, Patrick M Sexton, Laurence J Miller   +13 more
doaj   +1 more source

Microbiome affects mice metabolic homeostasis via differential regulation of gene expression in the brain and gut

Physiological Reports
The gut microbiome (GMB) regulates digestion, metabolism, immunity, and energy homeostasis. This study investigates how gut microbiota integrate the regulation in the neuroendocrine and enteroendocrine systems, with a focus on G protein‐coupled receptors
Wynne Milhouse, Anna Clapp Organski, Xun Sun, Derek Ai, Baohua Zhou, Tzu‐Wen L. Cross, Hongxia Ren   +6 more
doaj   +1 more source

Progress of Researches on Central Mechanism of Electroacupuncture Tolerance

针刺研究, 2016
Electroacupuncture(EA)has been demonstrated effective for pain relief.However,repeated application may decline analgesic effect of EA,which is termed EA tolerance,that reduces the clinical efficacy of EA.Therefore,it has attracted attention from ...
CUI Lu-ying, DING Ming-xing
doaj  

The physiology of the biliary tree. Motility of the gallbladder - Part 1

The Saudi Journal of Gastroenterology, 1999
An incomplete picture has emerged of the complex means by which gallbladder motility is controlled under normal and pathophysiological conditions. In the first part of this review an overall account is presented. The mechanisms of cholecystokinin release,
Ballal Mansour, Sanford Paul
doaj  

Heptahelical, G-Protein Linked Receptors (Cholecystokinin [CCK-A], Gastrin [CCK-B], Vasoactive Intestinal Polypeptide [VIP], Calcitonin Gene Related Polypeptide [CGRP], Pituitary Adenylate Cyclase Activating Polypeptide [PACAP])

, 1997
Stephen A Wank, Joseph R Pisegna
core   +1 more source

Correction: Evaluating the therapeutic efficacy of gastramide theranostics targeting cholecystokinin-2 receptors in a preclinical setting. [PDF]

RSC Adv
Rahimi MN, Pinson JA, Hilton-Proctor J, Van Zuylekom J, Blyth B, Roselt PD, Haskali MB.   +6 more
europepmc   +1 more source