Results 1 to 10 of about 70 (69)

Cholinergic Receptors in Cognitive Disorders [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1986
Abstract:Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have been examined in the hippocampus obtained at autopsy from a variety of patients with cognitive disorders (Alzheimer's, Parkinson's, and Huntington's diseases, Down's Syndrome and alcoholic dementia) and compared with neurologically normal controls and ...
Perry EK   +8 more
openaire   +2 more sources

Effect of gallamine on cholinergic receptors [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1970
Gallamine triethiodide causes tachycardia thought to be due to a specific vagolytic action. Recently, Brown and Crout have shown that gallamine may cause increased inotropic and chronotropic activity due to the release of catecholamines from cardiac sympathetic nerves.
F J, Rathbun, J T, Hamilton
openaire   +2 more sources

Acetylcholine and cholinergic receptors [PDF]

open access: yesBrain and Neuroscience Advances, 2019
This review provides a distillate of the advances in knowledge about the neurotransmitter functions of acetylcholine over the 50-year period between 1967 and 2017, together with incremental information about the cognate nicotinic and muscarinic acetylcholine receptors, and some brief comments on possible advances in the near future.
openaire   +3 more sources

Adrenergic and Cholinergic Receptors of Cerebral Microvessels [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 1981
The presence of α- and β-adrenergic and muscarinic cholinergic receptors in cerebral microvessels of the rat and pig was assessed by ligand binding techniques. The results demonstrate the presence of specific binding to α 2 - and β-adrenergic receptors but no appreciable specific binding to α
S I, Harik   +4 more
openaire   +2 more sources

Cholinergic receptor labelling specific irreversible binding of bromoacetylcholine to cholinergic receptors at neuromuscular junctions

open access: yesEuropean Journal of Pharmacology, 1974
This study shows that (a) the slopes of dose-response curves of bromoacetylcholine (BrACh) and acetylcoline (ACh) were the same; (b) the dose-response curves of BrACh to contract superfused chick biventer cervicis and frog rectus abdominis muscles were shifted to the right by d-tubocurarine in a parallel fashio; and (c) the responses of BrACh were not ...
Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, Florida 32610, U.S.A.   +1 more
openaire   +3 more sources

Cholinergic receptors in aging and Alzheimer's disease

open access: yesProgress in Neuro-Psychopharmacology and Biological Psychiatry, 1986
Although Alzheimer's disease (AD) is a disorder involving multiple neurotransmitter systems, the basal forebrain cholinergic system (Ch system) is severely and consistently affected in this condition. In both animals and man, the nature of age-associated alterations in the Ch system is unclear. In addition, available studies of cholinergic receptors in
P J, Whitehouse, K S, Au
openaire   +2 more sources

Muscarinic cholinergic receptors in rabbit retina

open access: yesJournal of Pharmacy and Pharmacology, 1985
Abstract Binding sites with high affinity and specificity for [3 H]-quinuclidinyl benzilate are present in rabbit retinal homogenates. Only one set of binding sites was detected with an apparent dissociation constant of 2.13 times 10−10 M and a density of 59.2 fmol mg−1 of protein.
M J, Neal, C, Dawson
openaire   +2 more sources

Biological Functions of Keratinocyte Cholinergic Receptors

open access: yesJournal of Investigative Dermatology Symposium Proceedings, 1997
Human epidermal keratinocytes possess cholinergic enzymes, which synthesize and degrade acetylcholine, and express both nicotinic and muscarinic classes of cholinergic receptors on their cell surfaces. These receptors bind acetylcholine and initiate cellular response.
openaire   +2 more sources

The Cholinergic Receptor

open access: yesJournal of Pharmacy and Pharmacology, 1960
openaire   +3 more sources

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