Results 1 to 10 of about 2,364,275 (293)
Acetylcholine and cholinergic receptors [PDF]
This review provides a distillate of the advances in knowledge about the neurotransmitter functions of acetylcholine over the 50-year period between 1967 and 2017, together with incremental information about the cognate nicotinic and muscarinic acetylcholine receptors, and some brief comments on possible advances in the near future.
D. Brown
openaire +5 more sources
A sex-specific effect of M4 muscarinic cholinergic autoreceptor deletion on locomotor stimulation by cocaine and scopolamine [PDF]
ObjectiveAcetylcholine modulates the activity of the direct and indirect pathways within the striatum through interaction with muscarinic M4 and M1 receptors.
Anna Berezovskaia+10 more
doaj +2 more sources
Beta-adrenergic and M-cholinergic receptor interactions in the pathogenesis of bronchial obstructive pulmonary diseases [PDF]
The crosstalk between the beta-2-adrenoceptor and M- cholinoreceptor systems in the airways plays one of the main roles in the pathogenesis of bronchoobstructive diseases.
Anna V. Eremenko, Kirill A. Zykov
doaj +1 more source
The human α7 nicotinic receptor is a pentameric channel mediating cellular and neuronal communication. It has attracted considerable interest in designing ligands for the treatment of neurological and psychiatric disorders. To develop a novel class of α7
Marie S. Prevost+11 more
doaj +1 more source
Nerve growth factor (NGF) receptors are evolutionary conserved molecules, and in mammals are considered necessary for ensuring the survival of cholinergic neurons.
Paolo de Girolamo+5 more
doaj +1 more source
Cholinergic Receptors in Cognitive Disorders [PDF]
Abstract:Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have been examined in the hippocampus obtained at autopsy from a variety of patients with cognitive disorders (Alzheimer's, Parkinson's, and Huntington's diseases, Down's Syndrome and alcoholic dementia) and compared with neurologically normal controls and ...
Perry EK+8 more
openaire +2 more sources
Effect of gallamine on cholinergic receptors [PDF]
Gallamine triethiodide causes tachycardia thought to be due to a specific vagolytic action. Recently, Brown and Crout have shown that gallamine may cause increased inotropic and chronotropic activity due to the release of catecholamines from cardiac sympathetic nerves.
John T. Hamilton, Flora J. Rathbun
openaire +3 more sources
Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types.
Kateryna Uspenska+6 more
doaj +1 more source
Acetylcholine and spinal locomotor networks: The insider
This article aims to review studies that have investigated the role of neurons that use the transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks within the spinal cord. This cholinergic system has the particularity of
Théo Mille+3 more
doaj +1 more source
Cholinergic Regulation of Hippocampal Theta Rhythm
Cholinergic regulation of hippocampal theta rhythm has been proposed as one of the central mechanisms underlying hippocampal functions including spatial memory encoding.
Zhenglin Gu, Jerrel L. Yakel
doaj +1 more source