Results 1 to 10 of about 79,884 (218)

Beta-adrenergic and M-cholinergic receptor interactions in the pathogenesis of bronchial obstructive pulmonary diseases [PDF]

Клиническая практика, 2020
The crosstalk between the beta-2-adrenoceptor and M- cholinoreceptor systems in the airways plays one of the main roles in the pathogenesis of bronchoobstructive diseases.
Anna V. Eremenko, Kirill A. Zykov
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An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies

Nature Communications, 2023
The human α7 nicotinic receptor is a pentameric channel mediating cellular and neuronal communication. It has attracted considerable interest in designing ligands for the treatment of neurological and psychiatric disorders. To develop a novel class of α7
Marie S. Prevost, Nathalie Barilone, Gabrielle Dejean de la Bâtie, Stéphanie Pons, Gabriel Ayme, Patrick England, Marc Gielen, François Bontems, Gérard Pehau-Arnaudet, Uwe Maskos, Pierre Lafaye, Pierre-Jean Corringer   +11 more
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Cholinergic System and NGF Receptors: Insights from the Brain of the Short-Lived Fish Nothobranchius furzeri

Brain Sciences, 2020
Nerve growth factor (NGF) receptors are evolutionary conserved molecules, and in mammals are considered necessary for ensuring the survival of cholinergic neurons.
Paolo de Girolamo, Adele Leggieri, Antonio Palladino, Carla Lucini, Chiara Attanasio, Livia D’Angelo   +5 more
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Mitochondrial Nicotinic Acetylcholine Receptors Support Liver Cells Viability After Partial Hepatectomy

Frontiers in Pharmacology, 2018
Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types.
Kateryna Uspenska, Olena Lykhmus, Maria Obolenskaya, Stephanie Pons, Uwe Maskos, Serhiy Komisarenko, Maryna Skok   +6 more
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Hippocampus and Entorhinal Cortex Recruit Cholinergic and NMDA Receptors Separately to Generate Hippocampal Theta Oscillations

Cell Reports, 2017
Summary: Although much progress has been made in understanding type II theta rhythm generation under urethane anesthesia, less is known about the mechanisms underlying type I theta generation during active exploration.
Zhenglin Gu, Georgia M. Alexander, Serena M. Dudek, Jerrel L. Yakel   +3 more
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Development of fetal nicotine and muscarinic receptors in utero

Brazilian Journal of Medical and Biological Research, 2007
The role of acetylcholine in the central and peripheral nervous systems is well established in adults. Cholinergic modulation of vascular functions and body fluid balance has been extensively studied.
C. Mao, J. Lv, H. Li, Y. Chen, J. Wu, Z. Xu   +5 more
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Acetylcholine and spinal locomotor networks: The insider

Physiological Reports, 2021
This article aims to review studies that have investigated the role of neurons that use the transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks within the spinal cord. This cholinergic system has the particularity of
Théo Mille, Camille Quilgars, Jean‐René Cazalets, Sandrine S. Bertrand   +3 more
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Cholinergic Regulation of Hippocampal Theta Rhythm

Biomedicines, 2022
Cholinergic regulation of hippocampal theta rhythm has been proposed as one of the central mechanisms underlying hippocampal functions including spatial memory encoding.
Zhenglin Gu, Jerrel L. Yakel
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The involvement of cholinergic neurons in the spreading of tau pathology

Frontiers in Neurology, 2013
Long time ago, it was described the selective loss of cholinergic neurons during the development of Alzheimer disease. Recently, it has been suggested that tau protein may play a role in that loss of cholinergic neurons through a mechanism involving the ...
Diana eSimon, Diana eSimon, Felix eHernandez, Felix eHernandez, Jesus eAvila, Jesus eAvila   +5 more
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Non-neuronal regulation and repertoire of cholinergic receptors in organs

Biomolecular Concepts, 2010
Many studies on the cholinergic pathway have indicated that cholinergic receptors, which are widely expressed in various cells, play an important role in all body organs.
Sato Tsuyoshi, Chida Dai, Iwata Takanori, Usui Michihiko, Hatori Kouki, Abe Takahiro, Takeda Shu, Yoda Tetsuya   +7 more
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