Results 11 to 20 of about 2,443,583 (255)
Regulators of cholinergic signaling in disorders of the central nervous system
Journal of Neurochemistry, 2021 Cholinergic signaling is crucial in cognitive processes, and degenerating cholinergic projections are a pathological hallmark in dementia. Use of cholinesterase inhibitors is currently the main treatment option to alleviate symptoms of Alzheimer's ...
Katarzyna Winek, H. Soreq, A. Meisel
semanticscholar +1 more source
Frontiers in Pharmacology, 2018 Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types.
Kateryna Uspenska +6 more
doaj +1 more source
Acta Pharmacologica Sinica, 2019 Midbrain dopaminergic (DA) neurons are governed by an endogenous cholinergic system, originated in the mesopontine nuclei. Nicotine hijacks nicotinic acetylcholine receptors (nAChRs) and interferes with physiological function of the cholinergic system ...
C. Xiao +3 more
semanticscholar +1 more source
Brain muscarinic cholinergic receptors in Huntington's disease [PDF]
, 1992 Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Agid, Y. +4 more
core +1 more source
A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
, 2004 An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, JC +5 more
core +5 more sources
Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. [PDF]
, 2013 Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system.
Krichmar, Jeffrey L, Zaldivar, Andrew
core +1 more source
Cell Reports, 2017 Summary: Although much progress has been made in understanding type II theta rhythm generation under urethane anesthesia, less is known about the mechanisms underlying type I theta generation during active exploration.
Zhenglin Gu +3 more
doaj +1 more source
Acetylcholine and spinal locomotor networks: The insider
Physiological Reports, 2021 This article aims to review studies that have investigated the role of neurons that use the transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks within the spinal cord. This cholinergic system has the particularity of
Théo Mille +3 more
doaj +1 more source
Development of fetal nicotine and muscarinic receptors in utero
Brazilian Journal of Medical and Biological Research, 2007 The role of acetylcholine in the central and peripheral nervous systems is well established in adults. Cholinergic modulation of vascular functions and body fluid balance has been extensively studied.
C. Mao +5 more
doaj +1 more source
Cholinergic Regulation of Hippocampal Theta Rhythm
Biomedicines, 2022 Cholinergic regulation of hippocampal theta rhythm has been proposed as one of the central mechanisms underlying hippocampal functions including spatial memory encoding.
Zhenglin Gu, Jerrel L. Yakel
doaj +1 more source