Results 11 to 20 of about 82,232 (263)

Non-neuronal regulation and repertoire of cholinergic receptors in organs

open access: yesBiomolecular Concepts, 2010
Many studies on the cholinergic pathway have indicated that cholinergic receptors, which are widely expressed in various cells, play an important role in all body organs.
Sato Tsuyoshi   +7 more
doaj   +1 more source

Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections

open access: yesmSphere, 2019
Acetylcholine modulates the virulence of Candida albicans and regulates an appropriate immune response to infection in a Galleria mellonella infection model. Indeed, the evidence suggests that C.
Christopher Nile   +11 more
doaj   +1 more source

Lack of an association between SNPs within the cholinergic receptor genes and smoking behavior in a Czech post-MONICA study [PDF]

open access: yesGenetics and Molecular Biology, 2014
Smoking has a significant heritable component of approximately 30-60%. Recent genome wide association studies have identified single nucleotide polymorphisms (SNPs) within the nicotinic cholinergic receptor subunits 3 (rs578776), 5 (rs16969968) and β3 ...
Jaroslav A. Hubacek   +2 more
doaj   +3 more sources

Selective cholinergic depletion in medial septum leads to impaired long term potentiation and glutamatergic synaptic currents in the hippocampus. [PDF]

open access: yesPLoS ONE, 2012
Cholinergic depletion in the medial septum (MS) is associated with impaired hippocampal-dependent learning and memory. Here we investigated whether long term potentiation (LTP) and synaptic currents, mediated by alpha-amino-3-hydroxy-5-methyl-isoxazole-4-
Patrick M Kanju   +7 more
doaj   +1 more source

Acetylcholine and cholinergic receptors [PDF]

open access: yesBrain and Neuroscience Advances, 2019
This review provides a distillate of the advances in knowledge about the neurotransmitter functions of acetylcholine over the 50-year period between 1967 and 2017, together with incremental information about the cognate nicotinic and muscarinic acetylcholine receptors, and some brief comments on possible advances in the near future.
openaire   +3 more sources

Cholinergic Stimulation of the Adult Zebrafish Brain Induces Phosphorylation of Glycogen Synthase Kinase-3 β and Extracellular Signal-Regulated Kinase in the Telencephalon

open access: yesFrontiers in Molecular Neuroscience, 2019
The sequencing of the zebrafish genome, the emergence of powerful gene-editing tools, and the development of in vivo imaging techniques have propelled the economical zebrafish into prominence as a biomedical research model.
Robert A. Mans   +5 more
doaj   +1 more source

Cholinergic receptor alterations in the cerebral cortex of spinal cord injured rat

open access: yesBiochemistry and Biophysics Reports, 2017
Many areas of the cerebral cortex process sensory information or coordinate motor output necessary for control of movement. Disturbances in cortical cholinergic system can affect locomotor coordination.
R. Chinthu, T.R. Anju, C.S. Paulose
doaj   +1 more source

Corelease of acetylcholine and GABA from cholinergic forebrain neurons

open access: yeseLife, 2015
Neurotransmitter corelease is emerging as a common theme of central neuromodulatory systems. Though corelease of glutamate or GABA with acetylcholine has been reported within the cholinergic system, the full extent is unknown.
Arpiar Saunders   +2 more
doaj   +1 more source

Axonal α7* nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections

open access: yesFrontiers in Neural Circuits, 2022
Modulation of the release of glutamate by activation of presynaptic nicotinic acetylcholine receptors (nAChRs) is one of the most prevalent mechanism of nicotinic facilitation of glutamatergic transmission in cortico-limbic circuits.
Chongbo Zhong   +3 more
doaj   +1 more source

Dopamine and Serotonin-Induced Modulation of GABAergic and Glutamatergic Transmission in the Striatum and Basal Forebrain

open access: yesFrontiers in Neuroanatomy, 2017
Catecholamine receptor-mediated modulation of glutamatergic or GABAergic transmission in the striatum as well as basal forebrain (BF) has been intensively studied during these two decades.
Toshihiko Momiyama, Takuma Nishijo
doaj   +1 more source

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