Results 191 to 200 of about 141,255 (305)
Time-dependent histological characterization of amyloid-β induced cholinergic and glial alterations and their modulation by dehydroepiandrosterone sulfate (DHEAS). [PDF]
Sólyomvári C +5 more
europepmc +1 more source
Heat acclimation improves the neural control of body temperature during heat stress in older adults
Abstract figure legend The neural control of body temperature during heat stress was compared between younger and older adults before and after 7 days of passive heat acclimation (hot water immersion; rectal temperature ≥38.5°C for 1 h). Pre‐acclimation, the onset threshold for increases in skin sympathetic nerve activity, cutaneous vascular ...
Thomas A. Deshayes +10 more
wiley +1 more source
Why acetylcholinesterase inhibitors should be considered disease-modifying drugs for Alzheimer's disease? [PDF]
Zuliani G +3 more
europepmc +1 more source
Abstract figure legend Obesity and metabolic syndrome (MetS) are well‐known major risk factors for overactive bladder (OAB). Mechanisms underlying obesity‐/MetS‐associated OAB were explored using a high‐fat‐diet (HFD)‐induced obesity mouse model. HFD‐induced obesity/MetS mice developed an OAB phenotype characterized by enlarged non‐voiding contractions
Ayu Sugiura +3 more
wiley +1 more source
Targeting muscarinic receptors for treating schizophrenia. [PDF]
Paul SM, Yohn SE.
europepmc +1 more source
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam +4 more
wiley +1 more source
Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale. [PDF]
Mogi M +4 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca +3 more
wiley +1 more source
Decoding the mechanisms of amyloid-β in synaptic toxicity. [PDF]
Toruński P +3 more
europepmc +1 more source

