Results 231 to 240 of about 653,806 (301)

Neural regulation of tumor immunity: emerging opportunities to enhance cancer immunotherapy. [PDF]

Exp Mol Med
Chen X, Zou M, Li N, Feng W, Lin P, Lin Y, Zhao X, Cui L.   +7 more
europepmc   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Intra-Accumbal Infusions of an α₂-Adrenoceptor Agonist and an α₂-Adrenoceptor Antagonist Respectively Inhibit and Enhance Acetylcholine but Not Dopamine Efflux in the Nucleus Accumbens of Freely Moving Rats. [PDF]

Synapse
Arai K, Kawashima H, Aono Y, Kosuge Y, Waddington JL, Saigusa T.   +5 more
europepmc   +1 more source

Severity of Cardiovascular Autonomic Neuropathy Is Linked to Increasing Levels of Circulating Proinflammatory Cytokines

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8847-8860, October 2026.
ABSTRACT Aims Cardiovascular autonomic neuropathy (CAN) is a severe form of diabetic neuropathy affecting approximately one in five people with diabetes and is a major predictor of cardiovascular mortality. Low‐grade inflammation may contribute to CAN development, but the exact inflammatory factors associated with CAN remain unclear.
Michelle Damgaard, Marietta Kokla, Rebekka H. Gerwig, Hatice Isik Mizrak, Sofie Korsgaard Hecquet, Tik Muk, Gurjeet Kaur, Birgitte Brock, Christian Stevns Hansen, Joachim Størling   +9 more
wiley   +1 more source

Varenicline-mediated cholinergic activation through α4β2 nAChR inhibits microglial neuroinflammation and alleviates neuropathic pain and depression following spinal cord injury. [PDF]

J Transl Med
Cheng L, Lai S, Wang Y, Zhu X, Song S, Lu DZ, Yang Y, Xu LL, Cai B, Wang J, Zeng H.   +10 more
europepmc   +1 more source

Neural regulation of tumor progression: implications for hepatocellular carcinoma. [PDF]

Front Immunol
Chen Y, Long Z, Zang YS, Wu D.
europepmc   +1 more source

Analysis of the Efficacy of Acetylcholinesterase Inhibitors in the Treatment of Alzheimer's Disease, Literature Review. [PDF]

Int J Mol Sci
Petrov W, Ślebioda D, Kozińska R, Kukla K, Petrov P, Sroka M, Tesyna J, Puźniak G, Kudliński M, Rejda T, Skowron I, Chłopaś-Konowałek A.   +11 more
europepmc   +1 more source

The sleep-wake cycle: molecular mechanisms, disorders, and therapeutic targets in the context of energy metabolism. [PDF]

Signal Transduct Target Ther
Li JK, Wang RY, Meng XY, Kang JS.
europepmc   +1 more source

Neural-immune-cardiovascular axis: from mechanistic crosstalk to therapeutic targets in cardiovascular disease. [PDF]

Front Immunol
Cheng J, Gao S, Zhang H, Gao W, Mei Z, Liu X, Gao J, Guo C, An G.   +8 more
europepmc   +1 more source