Results 51 to 60 of about 653,806 (301)

Brain‐Computer Interface Training Fosters Perceptual Skills to Detect Errors

Advanced Science, EarlyView.
Accurate perception of visuomotor errors underpins motor precision and learning, yet conventional behavioral training fails to improve sensitivity to subtle errors. Real‐time EEG‐based brain‐computer interface feedback targeting the error positivity component enhances perceptual learning of small errors.
Deland H. Liu, Fumiaki Iwane, Minsu Zhang, Leonardo G. Cohen, José del R. Millán   +4 more
wiley   +1 more source

Role of the thalamic parafascicular nucleus cholinergic system in the modulation of acute corneal nociception in rats [PDF]

Veterinary Research Forum, 2011
The present study investigated the effects of microinjections of acetylcholine (a cholinergic agonist), physostigmine (a cholinesterase inhibitor), atropine (an antagonist of muscarinic cholinergic receptors) and hexamethonium (an antagonist of nicotinic
Esmaeal Tamaddonfard, Amir-Abbas Farshid, Sona Seiednejhad, Asghar Morvaridi   +3 more
doaj  

Simultaneous release of glutamate and acetylcholine from single magnocellular "cholinergic" basal forebrain neurons [PDF]

, 2006
Basal forebrain (BF) neurons provide the principal cholinergic drive to the hippocampus and cortex. Their degeneration is associated with the cognitive defects of Alzheimer's disease. Immunohistochemical studies suggest that some of these neurons contain
Allen, TGJ, Abogadie, FC, Brown, DA
core  

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Cholinergic neurons in the dorsomedial hypothalamus regulate food intake

Molecular Metabolism, 2017
Objective: Central cholinergic neural circuits play a role in the regulation of feeding behavior. The dorsomedial hypothalamus (DMH) is considered the appetite-stimulating center and contains cholinergic neurons.
Jae Hoon Jeong, Dong Kun Lee, Young-Hwan Jo   +2 more
doaj   +1 more source

Does Cholinergic Stimulation Affect the P2X7 Receptor-Mediated Dye Uptake in Mast Cells and Macrophages?

Frontiers in Cellular Neuroscience, 2020
Background: Extracellular ATP is a powerful trigger of neuroinflammation by activating immune cells via P2X7 receptors. Acetylcholine and nicotinic agonists inhibit ATP-triggered proinflammatory cytokines via the so-called “cholinergic anti-inflammatory ...
Dilyara Nurkhametova, Dilyara Nurkhametova, Andrei Siniavin, Maria Streltsova, Denis Kudryavtsev, Igor Kudryavtsev, Igor Kudryavtsev, Raisa Giniatullina, Victor Tsetlin, Tarja Malm, Rashid Giniatullin, Rashid Giniatullin   +11 more
doaj   +1 more source

Noradrenergic and Cholinergic Reinnervation of Islet Grafts in Diabetic Rats [PDF]

, 1996
Grafted islets become denervated due to the islet transplantation procedure. The aim of the present study was 1) to examine whether islet grafts in the liver, the spleen, and under the kidney capsule in rats become reinnervated following the ...
Oestreicher, AB, Strubbe, JH, van der Zee, E A, Suylichem, Paul T.R. van,, Oestreicher, A B, Asperen, Roelie M. van,, Strubbe, Jan H.,, VanAsperen, RM, Steffens, Anton B.,, Houwing, H, van Suylichem, P T R, Eddy A. Van Der Zee, Steffens, AB, Zee, Eddy A. van der,, Harmina Houwing, VanderZee, EA, Strubbe, J H, Houwing, Harmina,, van Asperen, R M, Oestreicher, A. Beate,, Jan H. Strubbe, Van Suylichem, PTR, Paul T.R. Van Suylichem, Steffens, A B, Roelie M. Van Asperen, Asperen, Roelie M. van, A. Beate Oestreicher, Anton B. Steffens   +27 more
core   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

A sex-specific effect of M4 muscarinic cholinergic autoreceptor deletion on locomotor stimulation by cocaine and scopolamine

Frontiers in Molecular Neuroscience
ObjectiveAcetylcholine modulates the activity of the direct and indirect pathways within the striatum through interaction with muscarinic M4 and M1 receptors.
Anna Berezovskaia, Anna Berezovskaia, Morgan Thomsen, Morgan Thomsen, Morgan Thomsen, Anders Fink-Jensen, Anders Fink-Jensen, Anders Fink-Jensen, Gitta Wörtwein, Gitta Wörtwein, Gitta Wörtwein   +10 more
doaj   +1 more source

Brain muscarinic cholinergic receptors in Huntington's disease [PDF]

, 1992
Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Marsden, C. D., Jenner, P., Agid, Y., Lange, Klaus W., Javoy-Agid, F.   +4 more
core   +1 more source