Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Transcriptome, Proteome, and Metabolome Features in Diarrhea Challenge of Preweaning Piglets via Multi-Omics Integration Analyses. [PDF]
Zhao S, Peng S, Yang G, Yu H, Qiao S.
europepmc +1 more source
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Immune podocyte injury in autoimmune glomerular diseases. [PDF]
Zhu H, Sun J, Yan Y, Liu P, Huang Y.
europepmc +1 more source
Low-density lipoproteins in human serum competitively inhibit the binding and entry of vesicular stomatitis virus. [PDF]
Vandergaast R +6 more
europepmc +1 more source
Epstein-Barr virus receptors: classification, functional mechanisms, and pathogenic implications. [PDF]
Gu H +5 more
europepmc +1 more source
Targeting innate immunity to modulate bone metabolism: a novel strategy for osteoporosis treatment. [PDF]
Kou W +11 more
europepmc +1 more source
Nature-Inspired Alternatives to PEG for Next-Generation Long-Circulating Nanocarriers. [PDF]
Jan N, Rejili M.
europepmc +1 more source
Complement and inflammasome crosstalk in chronic inflammation. [PDF]
Janžič L, Kouter K.
europepmc +1 more source

