Results 101 to 110 of about 19,155 (223)

Developmental Plasticity and Behavioural Evolution in Rodents: Insights From African Striped Mice (Rhabdomys)

Journal of Zoology, EarlyView.
Our review synthesizes how early‐life experiences shape behavioural development in rodents, drawing on developmental plasticity, non‐genetic inheritance and epigenetic mechanisms. Using African striped mice (Rhabdomys) and other small mammal systems as case studies, it presents an integrative framework linking parental care, developmental pathways and ...
N. Pillay, T. L. Rymer
wiley   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

The Journal of Physiology, EarlyView.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus, Praveen Kumar, Kelly Kneale, T. Noah Hutson, Nicole M. Gautier‐Hall, Deng‐Shan Shiau, Megan Watts, Krystle Trosclair, Hemangini A. Dhaibar, Paari Dominic, Leonidas Iasemidis, Edward Glasscock   +11 more
wiley   +1 more source

Role of CRH in colitis and colitis-associated cancer: a combinative result of central and peripheral effects?

Frontiers in Endocrinology
Corticotropin-releasing factor family peptides (CRF peptides) comprise corticotropin releasing hormone (CRH), urocortin (UCN1), UCN2 and UCN3. CRH is first isolated in the brain and later with UCNs found in many peripheral cells/tissues including the ...
Chao Zhu, Shengnan Li
doaj   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Chronic Nicotine Consumption and Withdrawal Regulate Melanocortin Receptor, CRF, and CRF Receptor mRNA Levels in the Rat Brain

Brain Sciences
Alterations in the various neuropeptide systems in the mesocorticolimbic circuitry have been implicated in negative effects associated with drug withdrawal.
Oguz Gozen, Buket Aypar, Meliha Ozturk Bintepe, Fulya Tuzcu, Burcu Balkan, Ersin O. Koylu, Lutfiye Kanit, Aysegul Keser   +7 more
doaj   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Carbonyl stress markers are associated with binge‐eating/purging behavior of anorexia nervosa: A pilot study

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
This study investigated Advanced Glycation End Products (AGEs), reflecting carbonyl stress from glycation and oxidation reactions, as potential biomarkers for identifying binge‐eating/purging behaviors in anorexia nervosa (AN). Finding revealed higher fingertip AGE levels in the binge‐eating/purging subtype (ANBP) compared to the restricting subtype ...
Kana Morimoto, Masanori Isobe, Tomomi Noda, Keima Tose, Momo Sunada, Koichi Tabata, Momoka Taniguchi, Makoto Arai, Toshiya Murai   +8 more
wiley   +1 more source