Results 51 to 60 of about 21,979 (167)

Pleiotropic actions of allopregnanolone underlie therapeutic benefits in stress-related disease

Neurobiology of Stress, 2020
For several years, research from around the world has suggested that the neuroactive steroid (3α,5α)-3-hydroxypregnan-20-one (allopregnanolone) may have therapeutic potential for treatment of various stress-related diseases including post-traumatic ...
Giorgia Boero, Patrizia Porcu, A. Leslie Morrow   +2 more
doaj   +1 more source

Impact of Orexin-A Treatment on Food Intake, Energy Metabolism and Body Weight in Mice. [PDF]

PLoS ONE, 2017
Orexin-A and -B are hypothalamic neuropeptides of 33 and 28-amino acids, which regulate many homeostatic systems including sleep/wakefulness states, energy balance, energy homeostasis, reward seeking and drug addiction.
Anne Blais, Gaëtan Drouin, Catherine Chaumontet, Thierry Voisin, Anne Couvelard, Patrick Christian Even, Alain Couvineau   +6 more
doaj   +1 more source

Pharmacology and Biology of Corticotropin-Releasing Factor (CRF) Receptors

Receptors and Channels, 2002
The biology of corticotropin-releasing factor (CRF) finds increasing interest in the scientific community because of the neuromodulatory actions of CRF on brain functions such as learning, anxiety, feeding, and locomotion. Additional actions on immunumodulation and apoptosis have recently been discovered.
Eckart, K., Jahn, O., Radulovic, J., Radulovic, M., Blank, T., Stiedl, O., Brauns, O., Tezval, H., Zeyda, T., Spiess, J.   +9 more
openaire   +4 more sources

Immune Aspects and Myometrial Actions of Progesterone and CRH in Labor

Clinical and Developmental Immunology, 2012
Progesterone and corticotropin-releasing hormone (CRH) have a critical role in pregnancy and labor, as changes related to these hormones are crucial for the transition from myometrial quiescence to contractility.
Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Panayiotis Tsikouras, Zoe Iliodromiti   +4 more
doaj   +1 more source

Effects of epinephrine, corticotropin, and thyrotropin on lipolysis and glucose oxidation in rat adipose tissue

Journal of Lipid Research, 1967
(Log dose)-response curves have been determined for lipolysis and for the conversion of glucose-14C to 14CO2 by adipose tissue from rats in the presence of epinephrine, corticotropin, and thyrotropin.
George A. Bray
doaj   +1 more source

On the role of corticotropin-releasing hormone receptors in anxiety and depression

Dialogues in Clinical Neuroscience, 2002
On the basis of extensive basic and clinical studies, corticotropin-releasing hormone (CRH) and its related family members are considered to play a pivotal role in stress-related disorders, such as anxiety and depression. CRH is regarded as the principal mediator in the brain of the stress response, as it mediates neuroendocrine, autonomic, and ...
Reul, Johannes M H M, Holsboer, Florian
openaire   +3 more sources

Role and action mechanisms of tPA in CRH-induced apoptosis of mouse oviductal epithelial and mural granulosa cells

The Journal of Reproduction and Development
Understanding how stress hormones induce apoptosis in oviductal epithelial cells (OECs) and mural granulosa cells (MGCs) can reveal the mechanisms by which female stress impairs embryonic development and oocyte competence.
Yong-Qing YANG, Min ZHANG, Qi HUA, Rui-Jie MA, Xiao-Yan WANG, Hong-Jie YUAN, Ming-Jiu LUO, Jing-He TAN   +7 more
doaj   +1 more source

A molecular basis for the interaction of corticotropin with opiate receptors [PDF]

FEBS Letters, 1982
Snell, Christopher R., Snell, Penelope H.   +1 more
openaire   +2 more sources

Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells

Annals of Medicine
Background Stress-related hair loss is on the rise, largely due to escalating levels of stress-related corticotropin-releasing hormone (CRH) through poorly defined mechanisms.
Wenzi Liang, Xiuwen Chen, Na Ni, Chutong Zhuang, Zhiying Yu, Ziqing Xu, Yingshi Li, Changmin Lin, Keng Huang   +8 more
doaj   +1 more source

Skin Corticotropin-Releasing Hormone Receptor Expression in Psoriasis [PDF]

Journal of Investigative Dermatology, 2007
Tagen, Michael, Stiles, Linsey, Kalogeromitros, Demetrios, Gregoriou, Stamatios, Kempuraj, Duraisamy, Makris, Michael, Donelan, Jill, Vasiadi, Magdalini, Staurianeas, Nikolaos G., Theoharides, Theoharis C.   +9 more
openaire   +3 more sources