Results 41 to 50 of about 21,979 (167)

Function of Cannabinoid Receptors in the Neuroendocrine Regulation of Hormone Secretion

open access: yesNeurobiology of Disease, 1998
Marijuana and its cannabinoid constituents have profound effects on anterior pituitary hormone secretion. Exposure to Δ9-tetrahydrocannabinol inhibits gonadotropin, prolactin, growth hormone, and thyroid-stimulating hormone release and stimulates the ...
Laura L. Murphy   +3 more
doaj   +1 more source

Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The release of adrenocorticotropin (ACTH) from the corticotrophs is controlled principally by vasopressin and corticotropin-releasing hormone (CRH). Oxytocin may augment the release of ACTH under certain conditions, whereas atrial natriuretic peptide ...
McCann S.M.   +5 more
doaj  

Regulation of gonadotropins by corticotropin-releasing factor and urocortin

open access: yesFrontiers in Endocrinology, 2013
While stress activates the hypothalamic-pituitary-adrenal (HPA) axis, it suppresses the hypothalamic-pituitary-gonadal (HPG) axis. Corticotropin-releasing factor (CRF) is a major regulatory peptide in the HPA axis during stress.
Kazunori eKageyama
doaj   +1 more source

Corticotropin-releasing factor facilitates epileptiform activity in the entorhinal cortex: roles of CRF2 receptors and PKA pathway. [PDF]

open access: yesPLoS ONE, 2014
Whereas corticotropin-releasing factor (CRF) has been considered as the most potent epileptogenic neuropeptide in the brain, its action site and underlying mechanisms in epilepsy have not been determined.
Lalitha Kurada, Chuanxiu Yang, Saobo Lei
doaj   +1 more source

Involvement of Corticotropin-Releasing Factor and Receptors in Immune Cells in Irritable Bowel Syndrome

open access: yesFrontiers in Endocrinology, 2018
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder defined by ROME IV criteria as pain in the lower abdominal region, which is associated with altered bowel habit or defecation.
Mahanand Chatoo   +9 more
doaj   +1 more source

A novel role of peripheral corticotropin-releasing hormone (CRH) on dermal fibroblasts. [PDF]

open access: yesPLoS ONE, 2011
Corticotropin-releasing hormone, or factor, (CRH or CRF) exerts important biological effects in multiple peripheral tissues via paracrine/autocrine actions.
Olga Rassouli   +8 more
doaj   +1 more source

Hypothesis of the neuroendocrine cortisol pathway gene role in the comorbidity of depression, type 2 diabetes, and metabolic syndrome

open access: yesThe Application of Clinical Genetics, 2014
Claudia Gragnoli1,21Center for Biotechnology and Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA; 2Molecular Biology Laboratory, Bios Biotech Multi-Diagnostic Health Center, Rome, ItalyAbstract ...
Gragnoli C
doaj  

Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.

open access: yesPLoS ONE, 2011
A major obstacle in treating drug addiction is the severity of opiate withdrawal syndrome, which can lead to unwanted relapse. Mitragynine is the major alkaloid compound found in leaves of Mitragyna speciosa, a plant widely used by opiate addicts to ...
Beng-Siang Khor   +3 more
doaj   +1 more source

Ghrelin, via corticotropin‐releasing factor receptors, reduces glucose uptake and increases lipid content in mouse myoblasts cells

open access: yesPhysiological Reports, 2021
Ghrelin and the corticotropin‐releasing factor (CRF) family are known regulators of cellular metabolism and energy balance. We previously demonstrated that myoblast glucose metabolism is regulated by ghrelin and that this effect is mediated by CRF ...
Michal Elbaz, Eran Gershon
doaj   +1 more source

The Role of Corticotropin-Releasing Factor Receptors in Stress and Anxiety [PDF]

open access: yesIntegrative and Comparative Biology, 2002
Corticotropin releasing factor (CRF) is a critical integrator of the hypothalamic-pituitary-adrenal (HPA) axis in response to stress. CRF and its related molecule urocortin (UCN) bind CRF receptor 1 (CRFR1) and CRFR2 with distinct affinities. Mice deficient for CRFR1 or CRFR2 were generated in order to determine the physiological role of these ...
Tracy L, Bale   +2 more
openaire   +2 more sources

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