Results 21 to 30 of about 21,979 (167)

Urocortins in the mammalian endocrine system

open access: yesActa Veterinaria Scandinavica, 2019
Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family, are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body functions by binding to two G protein-coupled receptors: receptor type 1 ...
Caterina Squillacioti   +3 more
doaj   +1 more source

The Effects of Alcohol Intoxication and Withdrawal on Hypothalamic Neurohormones and Extrahypothalamic Neurotransmitters

open access: yesBiomedicines, 2023
The aim of the present study was to determine the effects of alcohol intoxication and withdrawal on hypothalamic neurohormones such as corticotropin-releasing factor (CRF) and arginine vasopressin (AVP), and extrahypothalamic neurotransmitters such as ...
Balázs Simon   +9 more
doaj   +1 more source

Chia seeds oil ameliorate chronic immobilization stress-induced neurodisturbance in rat brains via activation of the antioxidant/anti-inflammatory/antiapoptotic signaling pathways

open access: yesScientific Reports, 2023
Chronic immobilization stress plays a key role in several neuropsychiatric disorders. This investigation assessed the possible ameliorative effect of chia seed oil (CSO) against the neurodisturbance-induced in rats by chronic immobilization.
Norhan E. Khalifa   +7 more
doaj   +1 more source

Brain corticotropin releasing hormone and stress reactivity

open access: yesИнтегративная физиология, 2021
The hypothalamic-pituitary-adrenocortical axis is one of the main components of stress adaptation. Corticotropin-releasing hormone (CRH) coming from the nucleus paraventricularis hypothalami (PVN) is the canonical central regulator of the axis.
Krisztina Bánrévi   +6 more
doaj   +1 more source

Cooperative CRF and α1 Adrenergic Signaling in the VTA Promotes NMDA Plasticity and Drives Social Stress Enhancement of Cocaine Conditioning

open access: yesCell Reports, 2018
Summary: Stressful events rapidly trigger activity-dependent synaptic plasticity, driving the formation of aversive memories. However, it remains unclear how stressful experience affects plasticity mechanisms to regulate appetitive learning, such as ...
Jorge Tovar-Díaz   +4 more
doaj   +1 more source

Corticotropin Releasing Hormone Signaling in the Bed Nuclei of the Stria Terminalis as a Link to Maladaptive Behaviors

open access: yesFrontiers in Neuroscience, 2021
The bed nuclei of the stria terminalis (BST) is a limbic region in the extended amygdala that is heavily implicated in anxiety processing and hypothalamic-adrenal-pituitary (HPA) axis activation.
Claire Emily Young   +3 more
doaj   +1 more source

Distribution of Urocortins and Corticotropin-Releasing Factor Receptors in the Cardiovascular System

open access: yesInternational Journal of Endocrinology, 2012
Urocortins are human homologues of urotensin I, a fish corticotropin-releasing-factor- (CRF-) like peptide secreted from the urophysis. There are three urocortins: urocortin 1, urocortin 2, and urocortin 3 in mammals.
Kazuhiro Takahashi
doaj   +1 more source

The Local Neuropeptide System of Keratinocytes

open access: yesBiomedicines, 2021
Neuropeptides have been known for over 50 years as chemical signals in the brain. However, it is now well established that the synthesis of this class of peptides is not restricted to neurons. For example, human skin not only expresses several functional
Nicola Cirillo
doaj   +1 more source

Interaction between the hypothalamo-pituitary-adrenal and thyroid axes during immobilization stress

open access: yesFrontiers in Physiology, 2022
The location of corticotropin-releasing hormone receptor 2 (CRH-R2) on thyrotropes within the avian anterior pituitary (APit) and its activation by different stressors indicate a possible communication between hypothalamo-pituitary-adrenal (HPA) and ...
Hakeem J. Kadhim, Wayne J. Kuenzel
doaj   +1 more source

Pharmacogenetics of antidepressants

open access: yesFrontiers in Pharmacology, 2011
Up to 60% of depressed patients do not respond completely to antidepressants (AD) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes
Concetta eCrisafulli   +6 more
doaj   +1 more source

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