Results 1 to 10 of about 21,979 (167)

Modulation of Corticotropin-Releasing Hormone Receptor Expression During In Vitro Keratinocyte Differentiation [PDF]

Current Issues in Molecular Biology
Corticotropin-releasing hormone (CRH) and its receptors CRHR1 and CRHR2 are major actors in the stress response and are well established as components of the hypothalamic–pituitary–adrenal (HPA) axis.
Carole-Anne Martins, Sara Lesink, Angéline Roux, Guillaume Collet, Richard Daniellou   +4 more
doaj   +2 more sources

Catheterization of the petrosal sinus: possible advantage of desmopressin stimulation in Cushing disease [PDF]

Archives of Endocrinology and Metabolism
Thediagnosis of Cushing syndrome can be challenging, particularly when bilateral inferior petrosal sinus sampling (BIPSS) is required to differentiate ectopic tumors from pituitary adrenocorticotropic hormone (ACTH)-releasing tumors.
Heraldo Mendes Garmes, Sara Calazans de Siqueira, Karla Borges Daniel, Marilia Bortolotto Felippe Trentin, Mariana Tazima Fujiwara, Caroline Schinoll, Mateus Dal Fabbro, Fabio Rogerio, Leonardo Deus-Silva, Fabiano Reis   +9 more
doaj   +3 more sources

Neuroimmune connections between corticotropin-releasing hormone and mast cells: novel strategies for the treatment of neurodegenerative diseases

Neural Regeneration Research, 2021
Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis, which plays a major role in the body’s immune response to stress.
Piplu Bhuiyan, Yi-Wei Wang, Huan-Huan Sha, Hong-Quan Dong, Yan-Ning Qian   +4 more
doaj   +1 more source

Corticotropin-Releasing Hormone: Biology and Therapeutic Opportunities

Biology, 2022
In 1981, Wylie Vale, Joachim Spiess, Catherine Rivier, and Jean Rivier reported on the characterization of a 41-amino-acid peptide from ovine hypothalamic extracts with high potency and intrinsic activity stimulating the secretion of adrenocorticotropic ...
Alessandra Caruso, Alessandra Gaetano, Sergio Scaccianoce   +2 more
doaj   +1 more source

Expression and functional characterization of membrane-integrated mammalian corticotropin releasing factor receptors 1 and 2 in Escherichia coli. [PDF]

PLoS ONE, 2014
Corticotropin-Releasing Factor Receptors (CRFRs) are class B1 G-protein-coupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediators in the stress response.
Roberto Jappelli, Marilyn H Perrin, Kathy A Lewis, Joan M Vaughan, Christos Tzitzilonis, Jean E Rivier, Wylie W Vale, Roland Riek   +7 more
doaj   +1 more source

Functional characterization of two corticotropin-releasing hormone receptors in Larimichthys crocea

Frontiers in Marine Science, 2023
In the neuroendocrine system, corticotropin-releasing hormone (CRH) plays an important role in the hypothalamic–pituitary–adrenal/interrenal (HPA/HPI) axis. It exerts its effects by activating CRHRs, which belong to the class B G protein-coupled receptor
Xue Liu, Jiaqian Feng, Zhijing Jiang, Guangbo Zhang, Xiuwen Xu, Jixiu Wang, Jingwen Yang, Tianming Wang   +7 more
doaj   +1 more source

Moderate white light exposure enhanced spatial memory retrieval by activating a central amygdala-involved circuit in mice

Communications Biology, 2023
Light exposure can profoundly affect neurological functions and behaviors. Here, we show that short-term exposure to moderate (400 lux) white light during Y-maze test promoted spatial memory retrieval and induced only mild anxiety in mice.
MengJuan Shang, MeiLun Shen, RuoTong Xu, JingYu Du, JiMeng Zhang, Ding OuYang, JunZe Du, JunFeng Hu, ZhiChuan Sun, BingXia Wang, Qian Han, Yang Hu, YiHong Liu, Yun Guan, Jing Li, GuoZhen Guo, JunLing Xing   +16 more
doaj   +1 more source

The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response

Вавиловский журнал генетики и селекции, 2021
Stress is an essential part of everyday life. The neuropeptide corticotropin-releasing hormone (CRH, also called CRF and corticoliberin) plays a key role in the integration of neuroendocrine, autonomic and behavioral responses to stress.
E. V. Sukhareva
doaj   +1 more source

Mechanism of Anticonvulsant Action of ACTH

Pediatric Neurology Briefs, 2001
The hypothesis that systemic or intraventricular administration of corticotropin (ACTH) acts directly on limbic neurons to modulate corticotropin-releasing hormone (CRH) gene expression, independently of adrenal stimulation, was tested and confirmed in ...
J Gordon Millichap
doaj   +1 more source

Transcriptional regulation of corticotropin-releasing hormone gene in stress response

IBRO Reports, 2018
As a central player of the hypothalamic-pituitary-adrenal (HPA) axis, the corticotropin -releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) determine the state of HPA axis and play a key role in stress response.
Jiang-Ning Zhou, Hui Fang
doaj   +1 more source