Results 181 to 190 of about 11,764 (203)

The role of CXC chemokine ligand (CXCL)12‐CXC chemokine receptor (CXCR)4 signalling in the migration of neural stem cells towards a brain tumour

Neuropathology and Applied Neurobiology, 2009
Aims:It has been shown that neural stem cells (NSCs) migrate towards areas of brain injury or brain tumours and that NSCs have the capacity to track infiltrating tumour cells. The possible mechanism behind the migratory behaviour of NSCs is not yet completely understood.
Meulen, Annebet A. E. van der, Biber, Knut, Lukovac, Sabina, Balasubramaniyan, Veerakumar, den Dunnen, W. F. A., Boddeke, Erik, Mooij, J. J. A.   +6 more
openaire   +4 more sources

IL-8 amplifies CD40/CD154-mediated ICAM-1 production via the CXCR-1 receptor and p38-MAPK pathway in human renal proximal tubule cells

American Journal of Physiology-Renal Physiology, 2009
Activation of the CD40 receptor by its cognate ligand, CD154, results in interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) production and increased intercellular adhesion molecule-1 (ICAM-1) expression in proximal tubule cells (PTCs).
Hongye, Li, Edward P, Nord
openaire   +2 more sources

The therapeutic potential of a C‐X‐C chemokine receptor type 4 (CXCR‐4) antagonist on hypertrophic scarring in vivo

Wound Repair and Regeneration, 2014
AbstractEffective prevention and treatment of hypertrophic scars (HTSs), a dermal form of fibrosis that frequently occurs following thermal injury to deep dermis, are unsolved significant clinical problems. Previously, we have found that stromal cell‐derived factor 1/CXCR4 signaling is up‐regulated during wound healing in burn patients and HTS tissue ...
Jie, Ding, Zengshuan, Ma, Hongbin, Liu, Peter, Kwan, Takashi, Iwashina, Heather A, Shankowsky, Donald, Wong, Edward E, Tredget   +7 more
openaire   +2 more sources

The expression of chemokine receptors CCR6, CXCR2 and CXCR4 is not organ‐specific for distant metastasis in colorectal cancer: a comparative study

Histopathology, 2013
AimsThe liver and lung are the organs most commonly affected by metastasis in colorectal cancer (CRC), and the interaction of chemokines and chemokine receptors (CKRs) plays an important role in the metastatic process. The aim of this study was to investigate the organ specificity of CKRs in CRC distant metastasis.Methods and resultsSurgical specimens ...
Dongzhi, Hu, Changzheng, Du, Weicheng, Xue, Fangyuan, Dou, Yunfeng, Yao, Jin, Gu   +5 more
openaire   +2 more sources

Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression

Pharmacological Reports, 2014
Depression can be perceived as a psychoneuroimmunological disorder in which cytokines affecting the body's neurochemical and neuroendocrine functions play an important role. Among cytokines, chemokines participating in activation of the inflammatory response are considered to be crucial.160 men and women were enrolled in the study.
Ewa A. Ogłodek, Anna Szota, Marek J. Just, Danuta Moś, Aleksander Araszkiewicz   +4 more
openaire   +2 more sources

Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder

Pharmacological Reports, 2015
Posttraumatic stress disorder (PTSD) can be perceived as a psychoneuroimmunological disorder in which cytokines affecting the neurochemical and neuroendocrine functions of the body play an important role. Among cytokines, chemokines participating in activation of the inflammatory response are considered to be crucial.220 men and women were enrolled in ...
Ewa A. Ogłodek, Anna M. Szota, Danuta M. Moś, Aleksander Araszkiewicz, Adam R. Szromek   +4 more
openaire   +2 more sources

The therapeutic effect of IL-21 combined with IFN-γ inducing CD4+CXCR5+CD57+T cells differentiation on hepatocellular carcinoma

Journal of Advanced Research, 2022
Changlin Zhao
exaly  

Stem Cell Markers CXCR-4 and CD133 Predict Aggressive Phenotype and Their Double Positivity Indicates Poor Prognosis of Oral Squamous Cell Carcinoma

Cancers, 2021
Halagowder Devaraj
exaly  

Novel dichloroquinoxaline CXCR receptor antagonists

Expert Opinion on Therapeutic Patents, 2000
openaire   +1 more source

A SUBSET OF CD34+ HEMATOPOIETIC CELLS IN HIV-INFECTED INDIVIDUALS EXPRESS THE CD4, CXCR-4 AND CKR-5 RECEPTORS.

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1998
G R Simon, N K Banda, J S Sipple, E J Shpall, A M Myers, G S Harrison   +5 more
openaire   +1 more source