Results 211 to 220 of about 166,825 (267)

CD8+ T Lymphocytes in Pituitary Neuroendocrine Tumors: Friend or Foe? [PDF]

Cells
Nastase VN, Ceausu AR, Burcea IF, Dumitriu-Stan RI, Gaje PN, Zara F, Raica M, Albai O, Poiana C, Timar B.   +9 more
europepmc   +1 more source

Metabotropic Glutamate Receptor 3 Expression During Liver Disease Progression: Association with Inflammation and Cell Viability in Hepatocellular Carcinoma. [PDF]

Int J Mol Sci
García-Gaytán AC, Hernández-Abrego A, De Ita-Pérez D, de Los Ríos-Arellano E, Gámez E, Díaz-Muñoz M, Méndez I.   +6 more
europepmc   +1 more source

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Glucocorticoid receptor dimerization in the cytoplasm might be essential for nuclear localization

Biochemical and Biophysical Research Communications, 2021
The glucocorticoid receptor (GR) plays an important role in steroid-dependent regulation of metabolism, development, and the immune response in humans. Although GR is known to be activated by the binding of glucocorticoid, the mechanism of action is poorly understood. We investigated dimerization of GR in the cytoplasm and nuclear trans-localization in
Su-Jun Lee, Ryota Shizu, Masahiko Negishi   +2 more
openaire   +2 more sources

Cytoplasmic-nuclear trafficking of steroid hormone receptors

Trends in Endocrinology & Metabolism, 1993
The nuclear localization of most steroid hormone receptors reflects a dynamic process: the receptor constantly diffuses out of the nucleus and is reimported by an active mechanism. The outward movement from the nucleus of the receptors and of other nuclear proteins is also mediated by the nuclear localization signals.
A, Guiochon-Mantel, E, Milgrom
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Nuclear and cytoplasmic estrogen receptors and progesterone receptors in breast cancer

European Journal of Cancer (1965), 1980
The relationships of cytoplasmic estrogen receptors occupied and free nuclear estrogen receptors and cytoplasmic progesterone receptors measured in a series of 83 primary breast carcinoma were examined. 83% of the patients were postmenopausal (range in age 30-86 years; average age 59.7). Preparation of the cytosol and nuclear fractions were described
R, Hähnel, R K, Partridge, L, Gavet, E, Twaddle, T, Ratajczak   +4 more
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Cytoplasmic and Nuclear Estradiol and Progesterone Receptors in Human Endometrium*

The Journal of Clinical Endocrinology & Metabolism, 1978
Estradiol and progesterone receptors have been characterized in normal human endometrial biopsy samples. The cytosol and nuclei were prepared from 150-250-mg samples, either processed immediately or kept in liquid nitrogen. The total concentration of estradiol-and progesterone-binding sites (available or occupied with endogenous hormone) were measured ...
F, Bayard, S, Damilano, P, Robel, E E, Baulieu   +3 more
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Nuclear and cytoplasmic receptors for 1,25-dihydroxycholecalciferol in intestinal mucosa

Biochemical and Biophysical Research Communications, 1973
The apparent hormonal form of cholecalciferol, 1,25-dihydroxycholecalciferol (1,25-(OH)2-CC), was incubated with intestinal mucosa homogenates and whole intestinal tissue, in vitro. After 40–70 min, 1,25-(OH)2-CC was specifically associated with the nuclear chromatin fraction.
P F, Brumbaugh, M R, Haussler
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