Results 221 to 230 of about 166,825 (267)
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Binding of aldosterone to cytoplasmic and nuclear receptors of the rabbit kidney
American Journal of Physiology-Cell Physiology, 1981The binding characteristics of [3H]aldosterone ([3H]A) in the rabbit kidney were compared with those described in other species, and experimental conditions suitable for both the isolation of renal tubules and the retention of aldosterone receptors were examined.
N, Farman, A, Vandewalle, J P, Bonvalet
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Cytoplasmic and Nuclear Cytokine Receptor Complexes
1997Much of our understanding on how hormones and cytokines transmit their message into the cell is based on the receptor activation at the plasma membrane. Many experimental in vitro models have established the paradigm for cytokine action based upon such activation of their cell surface receptor.
H C, Mertani, G, Morel, P E, Lobie
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Ecdysteroid Receptors: A Comparison of Cytoplasmic and Nuclear Receptors from Crayfish Hypodermis
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1982Cytoplasmic and nuclear ecdysteroid receptors from intermolt Orconectes limosus integument have been compared. The specificities as well as the KD values for three [3H]ecdysteroids are very similar in both preparations. Using a photoaffinity labelling technique, the molecular mass of the hormone-receptor complexes from both preparations was determined ...
M, Londershausen +2 more
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Characteristics of Cytoplasmic and Nuclear Receptor Forms
1979Although this monograph is primarily concerned with the relationship between hormone-induced responses and nuclear binding, it is necessary to relate nuclear receptors to their cytoplasmic counterparts.
James H. Clark, Ernest J. Peck
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Are estrogen receptors cytoplasmic or nuclear? Some immunocytochemical and biochemical studies
Journal of Steroid Biochemistry, 1987The subcellular localization of estradiol receptor (ER) has been examined using various experimental approaches. Immunocytochemical studies using the monoclonal antibody JS 34/32, raised against calf uterine cytosolic ER, yielded only equivocal results. In general, cells and tissues pretreated with estradiol showed positive immunostaining in the nuclei
I, Parikh +4 more
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Characteristics of the cytoplasmic and nuclear dihydrotestosterone receptors of human thymic tissue
Steroids, 1983Dihydrotestosterone receptor was prepared from both the cytoplasm and nucleus of human thymic tissue. Human cytoplasmic and nuclear dihydrotestosterone receptor possessed a KA greater than 1.0 and by competition assay was highly specific for dihydrotestosterone.
C J, Grossman +2 more
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Nuclear and cytoplasmic lectin receptor sites in rat Py1a osteoblasts.
Histology and histopathology, 2000The intracellular distribution of lectin receptor sites was studied in the rat Pyla osteoblasts using immunofluorescence at the confocal microscopy level. This immortalized cell line was found to represent a satisfactory model to study the occurrence and distribution of sugar moieties.
SABBIETI, Maria Giovanna +3 more
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Cytoplasmic and nuclear signaling pathways of V1-vascular vasopressin receptors
Regulatory Peptides, 1993We studied the cytoplasmic and nuclear signaling pathways of V1-vascular AVP receptors of human platelets, primary cultures of renal glomerular mesangial cells, and established cultures of the A7r5 aortic smooth muscle cell line. The immediate transmembrane signals are triggered by the formation of ligand-receptor complexes as illustrated by binding ...
M, Thibonnier, A L, Bayer, Z, Leng
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Endocrinology, 1987
Using a monospecific, monoclonal antibody against the glucocorticoid receptor (GR), an immunocytochemical study was performed to investigate the intracellular localization of GR both in the presence or absence of ligand. With all fixation methods tested (paraformaldehyde, acetic acid in ethanol, Bouin's fixative, and bensochinone in PBS), it was ...
A C, Wikström +4 more
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Using a monospecific, monoclonal antibody against the glucocorticoid receptor (GR), an immunocytochemical study was performed to investigate the intracellular localization of GR both in the presence or absence of ligand. With all fixation methods tested (paraformaldehyde, acetic acid in ethanol, Bouin's fixative, and bensochinone in PBS), it was ...
A C, Wikström +4 more
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Gynecologic Oncology, 1990
Biopsies from 131 women with squamous cell carcinoma of the cervix diagnosed between May 1983 and July 1986 were assayed for nuclear and "cytoplasmic" estrogen receptors (NER and CER). Progesterone receptors (PR) were also assayed in 45 of these tumors. About a third of the tumors contained both CER and NER. One or the other fraction contained ER in 76.
J, Darne +3 more
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Biopsies from 131 women with squamous cell carcinoma of the cervix diagnosed between May 1983 and July 1986 were assayed for nuclear and "cytoplasmic" estrogen receptors (NER and CER). Progesterone receptors (PR) were also assayed in 45 of these tumors. About a third of the tumors contained both CER and NER. One or the other fraction contained ER in 76.
J, Darne +3 more
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