Results 251 to 260 of about 287,271 (313)

Impaired nucleocytoplasmic transport in SOD1-mediated ALS. [PDF]

Mol Neurodegener
Argueti-Ostrovsky S, Lim SM, Arogundade OA, Diaz-Garcia S, Yunisova G, Meng A, Hermann A, Ong K, Eremenko E, Bravo-Hernandez M, Driscoll SP, Lee CZ, Jiang X, Stavsky A, Barel S, Shani T, Kahn J, Pfaff SL, Monsonego A, Marsala M, Ravits J, Lagier-Tourenne C, Israelson A.   +22 more
europepmc   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Molecular Identification of <i>HR97</i> in the Swimming Crab <i>Portunus trituberculatus</i> and Its Potential Involvement in Ovarian Development. [PDF]

Biology (Basel)
Hou D, Bao Y, Chen Y, Zhou Q, Zhu X, Xie X, Zhu D.   +6 more
europepmc   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

RNF20 dynamically regulates RIG-I and MDA5 transcription and degradation via nucleocytoplasmic translocation to balance antiviral signaling. [PDF]

PLoS Pathog
Wang J, Liu Q, Zhao S, Shao Q, Fu F, Zhang K, Ma J, Wang Z, Yan Y, Wang H, Cheng Y, Sun J.   +11 more
europepmc   +1 more source

Hippo Signaling in the Lung: A Tale of Two Effectors-Yap Drives Airway Fate and Taz Drives Alveolar Differentiation. [PDF]

Cells
Warren R, De Langhe SPJ.
europepmc   +1 more source

Effects of increasing intranuclear calcium levels via MCU inhibition on mouse and human PSC-derived cardiomyocyte differentiation and maturation. [PDF]

Stem Cells Transl Med
Seo HJ, Kim JY, Cho HJ, Lee JE, Bang SB, Jeon M, Lee HA, Shin YJ, Yang HM, Kim HS.   +9 more
europepmc   +1 more source

Post-translational modifications of selective autophagy receptors: orchestrating cellular homeostasis, disease pathogenesis, and therapeutic opportunities. [PDF]

Cell Mol Biol Lett
Zhu W, Wang X, Li Q, Jiang X, Xu G.
europepmc   +1 more source

Biomarkers with Therapeutic or Prognostic Applications in Gynecologic Malignancies. [PDF]

Cancers (Basel)
Desouki MM, Mager KL.
europepmc   +1 more source