Results 261 to 270 of about 186,066 (336)

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source

Subverting Host Defense from Within: Innate Immune Modulation by <i>Coxiella burnetii</i>. [PDF]

Pathogens
Busbee AO, Arunima A, Samuel JE, van Schaik EJ.   +3 more
europepmc   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source

Molecular recognition in plant root endosymbiosis. [PDF]

Plant J
Fougner-Økland T, Spezzati M, Parys K.
europepmc   +1 more source

RNA export through the nuclear pore complex: pathways, mechanisms, and imaging strategies. [PDF]

RNA Biol
Fu D, Yu W, Zhang F, Rush C, Tingey M, Yang W.   +5 more
europepmc   +1 more source

XPO1: From basic research to clinical treatment (Review). [PDF]

Oncol Rep
Yang C, Zhu J, Zheng X, Hou X, Zhao J, Pan Y, Tang Y.   +6 more
europepmc   +1 more source

LKB1 attenuates the transport activity of GLUT1 by regulating the alternative splicing of PKM1/PKM2 in cervical cancer. [PDF]

J Gynecol Oncol
Wu M, Guo Y, Yang J, Wang E, Xu HT, Wu GP, Zhao H.   +6 more
europepmc   +1 more source

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Cytoplasmic and nuclear estradiol and progesterone receptors in human endometrium.

The Journal of Clinical Endocrinology & Metabolism, 1978
Estradiol and progesterone receptors have been characterized in normal human endometrial biopsy samples. The cytosol and nuclei were prepared from 150-250-mg samples, either processed immediately or kept in liquid nitrogen. The total concentration of estradiol-and progesterone-binding sites (available or occupied with endogenous hormone) were measured ...
F. Bayard, S. Damilano, P. Robel, E. Baulieu   +3 more
semanticscholar   +3 more sources

Characteristics of the cytoplasmic and nuclear dihydrotestosterone receptors of human thymic tissue.

Steroids, 1983
Dihydrotestosterone receptor was prepared from both the cytoplasm and nucleus of human thymic tissue. Human cytoplasmic and nuclear dihydrotestosterone receptor possessed a KA greater than 1.0 and by competition assay was highly specific for dihydrotestosterone.
C. Grossman, L. Sholiton, J. Helmsworth
semanticscholar   +3 more sources