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Cytoplasmic and nuclear progesterone receptors in the guinea pig uterus.
Endocrinology, 1976Although progesterone receptors have been studied in the uterine cytoplasm of many species, relatively little was known about the nuclear content of these binding proteins. In the present study, a nuclear progesterone receptor was deteced in the guinea pig uterus.
P D, Feil, C W, Bardin
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Heat Shock Proteins and the Cytoplasmic-Nuclear Trafficking of Steroid Receptors
1994Transcription factors, such as steroid receptors, must move through the cytoplasm to the nucleus and subsequently within the nucleus in a precisely targeted manner. Experiments carried out twenty years ago in intact cells exposed to metabolic inhibitors suggested that glucocorticoid receptors (GR) that have entered the nucleus (then defined as the low ...
William B. Pratt, Lawrence C. Scherrer
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Cancer research, 1981
The qualitative and quantitative relationships between cytoplasmic estrogen receptors (ERC), total nuclear estrogen receptors (ERN), and cytoplasmic progesterone receptors (PGR) in 74 primary and 23 metastatic human breast cancer tissues were studied.
R, Romić-Stojković, S, Gamulin
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The qualitative and quantitative relationships between cytoplasmic estrogen receptors (ERC), total nuclear estrogen receptors (ERN), and cytoplasmic progesterone receptors (PGR) in 74 primary and 23 metastatic human breast cancer tissues were studied.
R, Romić-Stojković, S, Gamulin
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Cytoplasmic and nuclear estrogen and progesterone receptors in male breast cancer.
Cancer research, 1982Cytoplasmic estrogen receptors were detected in 12 of 13 male breast cancer tumors. There was no significant correlation of receptor levels with the age of the patient, size and histological grading of the tumor, and stage and nodal involvement of the disease.
R J, Pegoraro, D, Nirmul, S M, Joubert
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Acta Endocrinologica, 1981
Abstract. The granulosa cells from immature rats were found to possess binding components for progestins. The physicochemical properties were determined. By sucrose gradient centrifugation, binding of [3H]R-5020 was observed in the 7S and 4S region of the gradient. Isoelectric focusing, however, revealed only one binding component (pH 5.9).
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Abstract. The granulosa cells from immature rats were found to possess binding components for progestins. The physicochemical properties were determined. By sucrose gradient centrifugation, binding of [3H]R-5020 was observed in the 7S and 4S region of the gradient. Isoelectric focusing, however, revealed only one binding component (pH 5.9).
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Cyclosporin A promotes nuclear transfer of a cytoplasmic progesterone receptor mutant.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1995The effects of cyclosporin A (CsA), FK506 and rapamycin (Rapa) on the intracellular localization of a mutated rabbit progesterone receptor (PR) which lacks the main constitutive nuclear localization signal (NLS) (delta 638-642) and is cytoplasmic in the absence of progesterone (Prog), were assayed by indirect immunofluorescence in Lcl3 cells, a mouse L-
I, Jung-Testas +3 more
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Gan, 1983
Nuclear estrogen receptors (ERN) were measured in human breast cancer and 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma using the dextran-coated charcoal method without addition of an adsorbing material such as hydroxyapatite. Cytoplasmic estrogen receptors (ERC), cytoplasmic progesterone receptors (PgR), and ERN were measured in 111 primary
R, Nishimura +3 more
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Nuclear estrogen receptors (ERN) were measured in human breast cancer and 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma using the dextran-coated charcoal method without addition of an adsorbing material such as hydroxyapatite. Cytoplasmic estrogen receptors (ERC), cytoplasmic progesterone receptors (PgR), and ERN were measured in 111 primary
R, Nishimura +3 more
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Interrelationships of nuclear and cytoplasmic estrogen receptors.
Current topics in developmental biology, 1972J, Gorski, G, Shyamala, D, Toft
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36. Cytoplasmic and nuclear aldosterone receptors in frog skin
Journal of Steroid Biochemistry, 1975M. Moguilewsky, J.P. Raynaud
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