Results 281 to 290 of about 186,066 (336)

Ecdysteroid Receptors: A Comparison of Cytoplasmic and Nuclear Receptors from Crayfish Hypodermis

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1982
Cytoplasmic and nuclear ecdysteroid receptors from intermolt Orconectes limosus integument have been compared. The specificities as well as the KD values for three [3H]ecdysteroids are very similar in both preparations. Using a photoaffinity labelling technique, the molecular mass of the hormone-receptor complexes from both preparations was determined ...
M, Londershausen, P, Kuppert, K D, Spindler   +2 more
openaire   +2 more sources

Characteristics of Cytoplasmic and Nuclear Receptor Forms

1979
Although this monograph is primarily concerned with the relationship between hormone-induced responses and nuclear binding, it is necessary to relate nuclear receptors to their cytoplasmic counterparts.
James H. Clark, Ernest J. Peck
openaire   +1 more source

Nuclear and cytoplasmic lectin receptor sites in rat Py1a osteoblasts.

Histology and histopathology, 2000
The intracellular distribution of lectin receptor sites was studied in the rat Pyla osteoblasts using immunofluorescence at the confocal microscopy level. This immortalized cell line was found to represent a satisfactory model to study the occurrence and distribution of sugar moieties.
SABBIETI, Maria Giovanna, MARCHETTI, Luigi, HURLEY M. M., MENGHI G.   +3 more
openaire   +3 more sources

Cytoplasmic and nuclear signaling pathways of V1-vascular vasopressin receptors

Regulatory Peptides, 1993
We studied the cytoplasmic and nuclear signaling pathways of V1-vascular AVP receptors of human platelets, primary cultures of renal glomerular mesangial cells, and established cultures of the A7r5 aortic smooth muscle cell line. The immediate transmembrane signals are triggered by the formation of ligand-receptor complexes as illustrated by binding ...
M, Thibonnier, A L, Bayer, Z, Leng
openaire   +2 more sources

Intracellular Localization of the Glucocorticoid Receptor: Evidence for Cytoplasmic and Nuclear Localization*

Endocrinology, 1987
Using a monospecific, monoclonal antibody against the glucocorticoid receptor (GR), an immunocytochemical study was performed to investigate the intracellular localization of GR both in the presence or absence of ligand. With all fixation methods tested (paraformaldehyde, acetic acid in ethanol, Bouin's fixative, and bensochinone in PBS), it was ...
A C, Wikström, O, Bakke, S, Okret, M, Brönnegård, J A, Gustafsson   +4 more
openaire   +2 more sources

Nuclear and “cytoplasmic” estrogen and progesterone receptors in squamous cell carcinoma of the cervix

Gynecologic Oncology, 1990
Biopsies from 131 women with squamous cell carcinoma of the cervix diagnosed between May 1983 and July 1986 were assayed for nuclear and "cytoplasmic" estrogen receptors (NER and CER). Progesterone receptors (PR) were also assayed in 45 of these tumors. About a third of the tumors contained both CER and NER. One or the other fraction contained ER in 76.
J, Darne, W P, Soutter, R, Ginsberg, F, Sharp   +3 more
openaire   +2 more sources

Interaction of the activated cytoplasmic glucocorticoid hormone receptor complex with the nuclear envelope

Biochemistry, 1981
Highly purified activated cytoplasmic glucocorticoid hormone receptor binds with high affinity to sites in the nuclear envelope. Nuclear envelope fragments can be isolated from purified chromatin. They bind activated cytoplasmic glucocorticoid receptor with the same equilibrium constant as nuclear envelopes.
P, Smith, C, von Holt
openaire   +2 more sources

Estrogen receptors of human endometrium: characterization of nuclear and cytoplasmic forms and comparisons with rat uterine receptors

Journal of Steroid Biochemistry, 1980
Abstract A controlled trypsinization procedure is reported which results in more efficient solubilization of the nuclear estrogen receptor from human endometrium and rat uterine tissue than does extraction with high salt (0.4 M KCl) alone. The trypsin-liberated nuclear receptors in both species sediment at 3–4S on both high and low salt gradients ...
B S, Katzenellenbogen, N C, Lan, S K, Rutledge   +2 more
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Intratumoral variation of cytoplasmic and nuclear estrogen receptor concentrations in human mammary carcinoma

European Journal of Cancer (1965), 1980
21 mastectomy specimens were investigated none of which had received preoperative radiation chemotherapy or endocrine therapy to determine the cytoplasmic and nuclear estradiol receptor content in different parts of human mammary carcinomas. The study found cytoplasmic-specific estradiol receptor values to vary widely but predictably throughout the ...
C, Silfverswärd, L, Skoog, S, Humla, S A, Gustafsson, B, Nordenskjöld   +4 more
openaire   +2 more sources

Nuclear‐cytoplasmic transport of EGFR involves receptor endocytosis, importin β1 and CRM1

Journal of Cellular Biochemistry, 2006
AbstractMany receptor tyrosine kinases (RTKs) can be detected in the cell nucleus, such as EGFR, HER‐2, HER‐3, HER‐4, and fibroblast growth factor receptor. EGFR, HER‐2 and HER‐4 contain transactivational activity and function as transcription co‐factors to activate gene promoters. High EGFR in tumor nuclei correlates with increased tumor proliferation
Hui-Wen, Lo, Mohamed, Ali-Seyed, Yadi, Wu, Geoffrey, Bartholomeusz, Sheng-Chieh, Hsu, Mien-Chie, Hung   +5 more
openaire   +2 more sources