Results 291 to 300 of about 299,088 (322)
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Binding of aldosterone to cytoplasmic and nuclear receptors of the rabbit kidney
American Journal of Physiology-Cell Physiology, 1981The binding characteristics of [3H]aldosterone ([3H]A) in the rabbit kidney were compared with those described in other species, and experimental conditions suitable for both the isolation of renal tubules and the retention of aldosterone receptors were examined.
N, Farman, A, Vandewalle, J P, Bonvalet
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Endocrinology, 1987
Using a monospecific, monoclonal antibody against the glucocorticoid receptor (GR), an immunocytochemical study was performed to investigate the intracellular localization of GR both in the presence or absence of ligand. With all fixation methods tested (paraformaldehyde, acetic acid in ethanol, Bouin's fixative, and bensochinone in PBS), it was ...
A C, Wikström +4 more
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Using a monospecific, monoclonal antibody against the glucocorticoid receptor (GR), an immunocytochemical study was performed to investigate the intracellular localization of GR both in the presence or absence of ligand. With all fixation methods tested (paraformaldehyde, acetic acid in ethanol, Bouin's fixative, and bensochinone in PBS), it was ...
A C, Wikström +4 more
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Journal of Pharmacology and Experimental Therapeutics, 2020
In mammals, 17β-estradiol (E2), the primary endogenous estrogen, maintains normal central nervous system (CNS) function throughout life and influences brain responses to injury and disease.
Maricedes Acosta-Martínez
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In mammals, 17β-estradiol (E2), the primary endogenous estrogen, maintains normal central nervous system (CNS) function throughout life and influences brain responses to injury and disease.
Maricedes Acosta-Martínez
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European Journal of Cancer (1965), 1980
21 mastectomy specimens were investigated none of which had received preoperative radiation chemotherapy or endocrine therapy to determine the cytoplasmic and nuclear estradiol receptor content in different parts of human mammary carcinomas. The study found cytoplasmic-specific estradiol receptor values to vary widely but predictably throughout the ...
C, Silfverswärd +4 more
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21 mastectomy specimens were investigated none of which had received preoperative radiation chemotherapy or endocrine therapy to determine the cytoplasmic and nuclear estradiol receptor content in different parts of human mammary carcinomas. The study found cytoplasmic-specific estradiol receptor values to vary widely but predictably throughout the ...
C, Silfverswärd +4 more
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Journal of Steroid Biochemistry, 1980
Abstract A controlled trypsinization procedure is reported which results in more efficient solubilization of the nuclear estrogen receptor from human endometrium and rat uterine tissue than does extraction with high salt (0.4 M KCl) alone. The trypsin-liberated nuclear receptors in both species sediment at 3–4S on both high and low salt gradients ...
B S, Katzenellenbogen +2 more
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Abstract A controlled trypsinization procedure is reported which results in more efficient solubilization of the nuclear estrogen receptor from human endometrium and rat uterine tissue than does extraction with high salt (0.4 M KCl) alone. The trypsin-liberated nuclear receptors in both species sediment at 3–4S on both high and low salt gradients ...
B S, Katzenellenbogen +2 more
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Gynecologic Oncology, 1990
Biopsies from 131 women with squamous cell carcinoma of the cervix diagnosed between May 1983 and July 1986 were assayed for nuclear and "cytoplasmic" estrogen receptors (NER and CER). Progesterone receptors (PR) were also assayed in 45 of these tumors. About a third of the tumors contained both CER and NER. One or the other fraction contained ER in 76.
J, Darne +3 more
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Biopsies from 131 women with squamous cell carcinoma of the cervix diagnosed between May 1983 and July 1986 were assayed for nuclear and "cytoplasmic" estrogen receptors (NER and CER). Progesterone receptors (PR) were also assayed in 45 of these tumors. About a third of the tumors contained both CER and NER. One or the other fraction contained ER in 76.
J, Darne +3 more
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Cytoplasmic and nuclear progesterone receptors in the guinea pig uterus.
Endocrinology, 1976Although progesterone receptors have been studied in the uterine cytoplasm of many species, relatively little was known about the nuclear content of these binding proteins. In the present study, a nuclear progesterone receptor was deteced in the guinea pig uterus.
P D, Feil, C W, Bardin
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Female breast carcinomas: nuclear and cytoplasmic proteins versus steroid receptors.
Cytobios, 2000Nuclear and cytoplasmic proteins of human female breast cancer were analysed by one-dimensional sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Oestrogen receptor and progesterone receptor expression was determined by semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) method.
M, Bryś +3 more
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Heat Shock Proteins and the Cytoplasmic-Nuclear Trafficking of Steroid Receptors
1994Transcription factors, such as steroid receptors, must move through the cytoplasm to the nucleus and subsequently within the nucleus in a precisely targeted manner. Experiments carried out twenty years ago in intact cells exposed to metabolic inhibitors suggested that glucocorticoid receptors (GR) that have entered the nucleus (then defined as the low ...
William B. Pratt, Lawrence C. Scherrer
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Cytoplasmic and nuclear estrogen and progesterone receptors in male breast cancer.
Cancer research, 1982Cytoplasmic estrogen receptors were detected in 12 of 13 male breast cancer tumors. There was no significant correlation of receptor levels with the age of the patient, size and histological grading of the tumor, and stage and nodal involvement of the disease.
R J, Pegoraro, D, Nirmul, S M, Joubert
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