Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss, characterised by the dysfunction and death of the photoreceptors and retinal pigment epithelium (RPE). Innate immune cell activation and accompanying para-inflammation
Alice Brandli +2 more
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Death Domain Interactions in Death Receptor Signaling
Laura M. Bender ., Andrew Thorburn .
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A simple and broadly applicable nanobody-based approach to generate potent TNFR agonists. [PDF]
Lang I +16 more
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Molecular neurobiological insights on integrative role of Trk neurotrophic receptors and their small-molecule agonists in neurodegenerative conditions. [PDF]
Sanjai M +5 more
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The trinity of T cell engagement: navigating the molecular and clinical landscape of CAR-T, TILs, and TCEs in the war against cancer. [PDF]
Yang Q, Wang S, Liu F, Yu Y, Zhao H.
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Subverting Host Defense from Within: Innate Immune Modulation by <i>Coxiella burnetii</i>. [PDF]
Busbee AO +3 more
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A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies. [PDF]
Frisby D +3 more
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Danger or Salvation? The Role of DAMPs in Cancer Therapy. [PDF]
Vedunova AA +4 more
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Stress-Dependent NF-κB Signaling in Acute Kidney Injury: Linking Inflammation, Autophagy, and Apoptosis. [PDF]
Kumar D.
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Focus on necroptosis: its role in the pathogenesis and therapeutic potential of osteoarthritis. [PDF]
Ouyang Y, Liao H, Kang W, Li F, Shen H.
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