Results 11 to 20 of about 292,990 (265)
NMR structure of the death domain of the p75 neurotrophin receptor [PDF]
EMBO Journal, 1997 The intracellular domain of the p75 neurotrophin receptor (p75ICD) lacks catalytic activity but contains a motif similar to death domains found in the cytoplasmic regions of members of the tumor necrosis factor receptor family and their downstream targets.
Gottfried Otting +2 more
exaly +3 more sources
NOD-like receptor repertoire in the chromosome-level genome of the demosponge Dysidea avara (Schmidt, 1862) [PDF]
Frontiers in ImmunologyPorifera, one of the earliest diverging metazoans, have shown a surprisingly complex immune repertoire. However, most information to date is based on de novo transcriptome assemblies, limiting our knowledge regarding the presence and evolution of ...
Vasiliki Koutsouveli +10 more
doaj +2 more sources
Role of Glycans on Key Cell Surface Receptors That Regulate Cell Proliferation and Cell Death
Cells, 2021 Cells undergo proliferation and apoptosis, migration and differentiation via a number of cell surface receptors, most of which are heavily glycosylated.
Yin Gao +3 more
doaj +1 more source
Frontiers in Immunology, 2021 Both plants and animals are endowed with sophisticated innate immune systems to combat microbial attack. In these multicellular eukaryotes, innate immunity implies the presence of cell surface receptors and intracellular receptors able to detect danger ...
Thibault Roudaire +7 more
doaj +1 more source
Regulation of anoikis by extrinsic death receptor pathways
Cell Communication and Signaling, 2023 Metastatic cancer cells can develop anoikis resistance in the absence of substrate attachment and survive to fight tumors. Anoikis is mediated by endogenous mitochondria-dependent and exogenous death receptor pathways, and studies have shown that caspase-
Ying-Hao Han +5 more
doaj +1 more source
Structure-function analysis of barley NLR immune receptor MLA10 reveals its cell compartment specific activity in cell death and disease resistance. [PDF]
PLoS Pathogens, 2012 Plant intracellular immune receptors comprise a large number of multi-domain proteins resembling animal NOD-like receptors (NLRs). Plant NLRs typically recognize isolate-specific pathogen-derived effectors, encoded by avirulence (AVR) genes, and trigger ...
Shiwei Bai +11 more
doaj +1 more source
A novel motif identified in dependence receptors. [PDF]
PLoS ONE, 2007 Programmed cell death signaling is a critical feature of development, cellular turnover, oncogenesis, and neurodegeneration, among other processes.
Gabriel del Rio +3 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2020 Nucleotide-binding leucine-rich repeat receptors (NLRs) are the most abundant type of immune receptors in plants and can trigger a rapid cell-death (hypersensitive) response upon sensing pathogens. We previously cloned the wheat NLR Sr35, which encodes a
Stephen Bolus +3 more
doaj +1 more source
Enzymatic Functions for Toll/Interleukin-1 Receptor Domain Proteins in the Plant Immune System
Frontiers in Genetics, 2020 Rationally engineered improvements to crop plants will be needed to keep pace with increasing demands placed on agricultural systems by population growth and climate change.
Adam M. Bayless, Marc T. Nishimura
doaj +1 more source
Role of ADGRG1/GPR56 in Tumor Progression
Cells, 2021 Cellular communication plays a critical role in diverse aspects of tumorigenesis including tumor cell growth/death, adhesion/detachment, migration/invasion, angiogenesis, and metastasis.
Kwai-Fong Ng +3 more
doaj +1 more source