Results 161 to 170 of about 2,526,995 (288)

Tonic dopamine and biases in value learning linked through a biologically inspired reinforcement learning model. [PDF]

Nat Commun
Romero Pinto S, Uchida N.
europepmc   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

Advanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai, Xiaoyi Shi, Xiao Liu, Xiaotong Gu, Wenting Li, Xiangjun Chen, Wei Hong   +6 more
wiley   +1 more source

PACAP Signalling Network in the Nucleus Accumbens Core Regulates Reinstatement Behaviour in Rat. [PDF]

Addict Biol
Bose S, Simandl G, Hess EM, Kong L, Raddatz NJ, Maunze B, Choi S, Baker DA.   +7 more
europepmc   +1 more source

Hyperprolactinemia and the Dopamine Receptor [PDF]

US Endocrinology, 2006
openaire   +3 more sources

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

mGlu2 Receptors in the Basal Ganglia: A New Frontier in Addiction Therapy. [PDF]

Front Biosci (Landmark Ed)
Mao LM, Puthumana E, Wang JQ.
europepmc   +1 more source

SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding

Advanced Science, EarlyView.
SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui, Yong Zhao, Canqun Yang, Tao Tang, Xiangke Liao, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuansong Zeng   +8 more
wiley   +1 more source

Dopamine D2 Receptors and Its Downstream Signaling in Compulsive Eating. [PDF]

Brain Sci
Leung C, Lutfy K.
europepmc   +1 more source

Targeting Fibrotic Scarring by Mechanoregulation of Il11ra1+/Itga11+ Fibroblast Patterning Promotes Axon Growth after Spinal Cord Injury

Advanced Science, EarlyView.
This study demonstrates that a hydrogel with mechanical properties matching the spinal cord directs fibroblast alignment, reshaping fibrotic scars into parallel matrices. A specific fibroblast subset mediates extracellular matrix remodeling through mechanotransduction, promoting axonal regeneration and neural reconnections, revealing potential ...
Longyou Xiao, Kaixi Shi, Wen Li, Jialin Liu, Pengfei Xie, Zijun Hu, Yu Dai, Haiyan Weng, Qiuju Yuan, Wutian Wu, Limin Rong, Liumin He   +11 more
wiley   +1 more source

Neuroendocrinology meets addiction: Emerging pharmacotherapies on the horizon. [PDF]

J Intern Med
Loften A, Farokhnia M, Vendruscolo LF, Leggio L.   +3 more
europepmc   +1 more source