Results 91 to 100 of about 147,933 (225)

Dopamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]

, 2019
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [363]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is ...
Arvid Carlsson, Bernard Scatton, David K. Grandy, David R. Sibley, Emiliana Borrelli, Gilberto Fisone, Goran Sedvall, Hubert H. M. Van Tol, Jean-Charles Schwartz, Jean-Martin Beaulieu, John W. Kebabian, Kim A. Neve, Marc G. Caron, Maria Cristina Missale, Olivier Civelli, Philip Seeman, Pierre F. Spano, Pierre Sokoloff, Raul R. Gainetdinov, Saloman Z. Langer, Stefano Espinoza   +20 more
core   +2 more sources

Pharmacological Evidence That Dopamine Inhibits the Cardioaccelerator Sympathetic Outflow via D2-Like Receptors in Pithed Rats

Journal of Pharmacological Sciences, 2013
It has been suggested that N,N-di-n-propyl-dopamine (dopamine analogue) decreased heart rate in rats through stimulation of dopamine receptors. Nevertheless, the role of prejunctional dopamine D1/2-like receptors or even α2-adrenoceptors to mediate ...
Oscar Alcántara-Vázquez, Ma. Trinidad Villamil-Hernández, Araceli Sánchez-López, David Centurión   +3 more
doaj  

Probing Cortical Sites of Antipsychotic Drug Action with in vivo Receptor Imaging

Behavioural Neurology, 2000
Imaging receptors using radioactive ligands has allowed direct determination of the sites of action of antipsychotic drugs. Initial studies relating antipsychotic drug efficacy to action at striatal dopamine D2-like receptors have recently been ...
P. Shaw, L. S. Pilowsky
doaj   +1 more source

The regulation of D2 dopamine receptor expression [PDF]

Molecular Psychiatry, 1998
The question of whether or not there is a polymorphism in or near DRD2 which is associated with receptor density remains unanswered. Both clinical and animal data demonstrate that D 2 dopamine receptor density is highly variable among individuals; differences of more than 100% are not uncommon. Among inbred mouse strains and F 2 intercrosses produced
openaire   +2 more sources

Physiological and Functional Basis of Dopamine Receptors and Their Role in Neurogenesis: Possible Implication for Parkinson’s disease

Journal of Experimental Neuroscience, 2018
Dopamine controls various physiological functions in the brain and periphery by acting on its receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors involved in the regulation of motor activity and several neurological ...
A. Mishra, Sonu Singh, S. Shukla
semanticscholar   +1 more source

Mesolimbic dopamine D2 receptor plasticity contributes to stress resilience in rats subjected to chronic mild stress

Psychopharmacology, 2013
RationaleFew studies have investigated neurobiological and biochemical differences between stress-resilient and stress-vulnerable experimental animals.ObjectivesWe investigated alterations in mesolimbic dopamine D2 receptor density and mRNA expression ...
D. Żurawek, A. Faron-Górecka, M. Kusmider, M. Kolasa, P. Gruca, M. Papp, M. Dziedzicka-Wasylewska   +6 more
semanticscholar   +1 more source

Regulation of Fear Extinction in the Basolateral Amygdala by Dopamine D2 Receptors Accompanied by Altered GluR1, GluR1-Ser845 and NR2B Levels

Frontiers in Behavioral Neuroscience, 2017
The amygdala, a critical structure for both Pavlovian fear conditioning and fear extinction, receives sparse but comprehensive dopamine innervation and contains dopamine D1 and D2 receptors.
Yan-Wei Shi, Yan-Wei Shi, Yan-Wei Shi, Bu-Fang Fan, Li Xue, Li Xue, Li Xue, Jia-Ling Wen, Hu Zhao, Hu Zhao, Hu Zhao   +10 more
doaj   +1 more source

Tetrahydrocannabinol and dopamine D1 receptor

Frontiers in Neuroscience
Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1
Jiwon Lee
doaj   +1 more source

The Blockade of D1/D2-Like Dopamine Receptors within the Dentate Gyrus of Hippocampus Decreased the Reinstatement of Morphine-Extinguished Conditioned Place Preference in Rats

Basic and Clinical Neuroscience, 2015
Introduction: The hippocampus (HIP), the primary brain structure related to learning and memory, receives sparse but comprehensive dopamine innervations and contains dopamine D1/D2-like receptors.
Behrooz Khakpour-Taleghani, Zahra Reisi, Abbas Haghparast   +2 more
doaj  

ITI-007 demonstrates brain occupancy at serotonin 5-HT2A and dopamine D2 receptors and serotonin transporters using positron emission tomography in healthy volunteers

, 2015
© 2015 Springer-Verlag Berlin Heidelberg.Rationale: Central modulation of serotonin and dopamine underlies efficacy for a variety of psychiatric therapeutics.
Bisuna, B, Brašić, JR, Davis, RE, Gapasin, L, Goldwater, DR, Guevara, MR, Kumar, A, Mates, S, Raymont, V, Vanover, KEE, Willis, W, Wong, DF, Ye, W, Zhou, Y   +13 more
core   +1 more source