Results 91 to 100 of about 39,913 (215)

Modulatory Effects of Dopamine D2 Receptors on Spreading Depression in Rat Somatosensory Neocortex

Basic and Clinical Neuroscience, 2014
Introduction: Spreading depression (SD) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex.
Anna Maria Haarmann, Maryam Jafarian, Fariba Karimzadeh, Ali Gorji   +3 more
doaj  

Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts)

Neurogastroenterology &Motility, EarlyView.
Anesthesia can alter measurements during digestive endoscopies, yet no standardized protocol currently exists. Two expert groups—the French Neuro‐Gastroenterology Group (GFNG) and anesthesiologists—used the Delphi method to reach a consensus on which drugs have an influence (91 amendments), ultimately resulting in a proposed anesthesia protocol (28 ...
Domitille Renard, Thomas Clavier, Osama Abou‐Arab, Gérard Amarenco, Emmanuel Besnier, Alice Blet, Matthieu Boisson, Charlène Brochard, Benoit Coffin, Audrey De Jong, Denis Frasca, Marc Garnier, Aurelie Gouel, Jérémie Jacques, Arthur James, Yoann Launey, Anne‐Marie Leroi, Chloé Melchior, Daphné Michelet, François Mion, Maxime Nguyen, Emmanuel Rineau, Amélie Rollé, Sabine Roman, Stéphanie Sigaut, Heithem Soliman, Fabien Wuestenberghs, Frank Zerbib, Guillaume Gourcerol, Charlotte Desprez   +29 more
wiley   +1 more source

Effects of Yoga Nidra on Stress, Anxiety, and Depression: A Systematic Review and Meta‐Analysis

Annals of the New York Academy of Sciences, EarlyView.
ABSTRACT The global mental health crisis has escalated to unprecedented levels, with stress, anxiety, and depression posing major public health concerns. Conventional interventions have shown limited success in addressing these multifaceted issues, prompting researchers to explore alternative solutions.
Shashank Ghai, Pawel Odyniec, Ishan Ghai
wiley   +1 more source

Dissecting Dopamine D2 Receptor Signaling

, 2015
Dopamine D2 receptor (D2R) is a G protein-coupled receptor (GPCR) that activates G protein and arrestin signaling molecules. D2R antagonism has been a hallmark of antipsychotic medications for more than half a century. However, this drug-class is associated with substantial side effects that decrease quality of life and medication compliance.
openaire   +2 more sources

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

Psychiatry and Clinical Neurosciences, EarlyView.
Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang, Kubra Trabzonlu, Emily Fullard Jones, Yasir Ahmed Syed   +3 more
wiley   +1 more source

Outcome and Toxicity Profile of Stereotactic Body Radiation Therapy for Adrenal Tumours in Dogs

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Stereotactic body radiation therapy (SBRT) has become a non‐invasive alternative option for canine adrenal tumours with high surgical risks; however, its clinical benefits and risks are still to be fully understood. The goal of this multi‐institutional retrospective study was to describe the clinical outcome and safety of SBRT for the ...
Lily Thorsen, Kimberley Law, Jillian Walz, Valerie Morales Coll, Ada Naramor, Charles Maitz, Lyndsay Kubicek, Zebulon Thorsen, Jishnu Rao Gutti, Marilia Takada   +9 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Psychotropic medication and the fetal brain

The Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source