Results 131 to 140 of about 111,594 (254)

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

De Novo Expression of Dopamine D2 Receptors on Microglia after Stroke

Journal of Cerebral Blood Flow and Metabolism, 2015
J. Huck, D. Freyer, C. Böttcher, M. Mladinov, Claudia Muselmann-Genschow, M. Thielke, N. Gladow, Dana Bloomquist, P. Mergenthaler, Josef Priller   +9 more
semanticscholar   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Dual cholinergic and serotonergic excitatory pathways mediate oxygen sensing in the zebrafish gill

The Journal of Physiology, EarlyView.
Abstract figure legend The present study identified two sub‐populations of gill oxygen sensing neuroepithelial cells (NECs) distinguishable by their stored neurotransmitters – serotonin (5‐hydroxytryptamine, 5‐HT) or acetylcholine (ACh). Using transgenic Tg(elavl3:GCaMP6s) zebrafish, which express an endogenous calcium reporter in neurons, we ...
Maddison Reed, Anthea A. Mavridis, Jan A. Mennigen, Michael G. Jonz   +3 more
wiley   +1 more source

Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV

Journal of Neuroinflammation
The catecholamine neurotransmitter dopamine is classically known for regulation of central nervous system (CNS) functions such as reward, movement, and cognition. Increasing evidence also indicates that dopamine regulates critical functions in peripheral
Stephanie M. Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A. Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C. M. Schlachetzki, Howard S. Fox, Peter J. Gaskill   +16 more
doaj   +1 more source

Does Adjuvant Metformin Reduce Olanzapine‐Induced Metabolic Adverse Effects in Patients Diagnosed With Schizophrenia

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
This systematic review evaluates the efficacy of adjunctive metformin in reducing metabolic adverse effects in patients with schizophrenia treated with olanzapine. Findings indicate metformin consistently improves weight, BMI, insulin resistance, triglycerides, and liver fat content, though effects on waist circumference and cholesterol remain variable,
Aquib Butt, Soban Sadiq
wiley   +1 more source

Role of Dopamine D2 Receptors in Human Reinforcement Learning

Neuropsychopharmacology, 2014
C. Eisenegger, Michael Naef, A. Linssen, L. Clark, P. K. Gandamaneni, U. Müller, T. Robbins   +6 more
semanticscholar   +1 more source

Prefronto‐thalamic hypoconnectivity in schizophrenia: Monkey to human translation of critical pathways for symptom‐related functions

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim Recent advances in genetic neuromodulation technology have enabled circuit‐specific interventions in nonhuman primates (NHPs), thereby revealing the causal functions of specific neural circuits. Using this technology, we recently identified in NHPs the causal roles of the dorsolateral prefrontal cortex (DLPFC) to the lateral part of the ...
Noriaki Yahata, Toshiyuki Hirabayashi, Takafumi Minamimoto   +2 more
wiley   +1 more source

Risk of diabetes mellitus with olanzapine compared to clozapine: A systematic review and meta‐analysis

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim Olanzapine and clozapine are second‐generation antipsychotics commonly associated with metabolic side effects. In Japan, olanzapine is designated as “principally contraindicated” for patients with diabetes, while clozapine is “used with caution,” despite similar pharmacological profiles.
Keigo Onda, Rizal Ichwansyah, Shuken Boku   +2 more
wiley   +1 more source

Aversive behavior induced by optogenetic inactivation of ventral tegmental area dopamine neurons is mediated by dopamine D2 receptors in the nucleus accumbens

Proceedings of the National Academy of Sciences of the United States of America, 2014
Teruko Danjo, K. Yoshimi, K. Funabiki, Satoshi Yawata, S. Nakanishi   +4 more
semanticscholar   +1 more source