Results 61 to 70 of about 41,424 (223)

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Evidence for dopamine production and distribution of dopamine D2 receptors in the equine gastrointestinal mucosa and pancreas.

PLoS ONE
Insulin dysregulation in horses is characterised by hyperinsulinaemia and/or tissue insulin resistance and is associated with increased risk of laminitis.
Nicolas C Galinelli, Nicholas J Bamford, Melody A de Laat, Martin N Sillence, Patricia A Harris, Simon R Bailey   +5 more
doaj   +1 more source

Characterisation of AmphiAmR11, an amphioxus (Branchiostoma floridae) D2-dopamine-like G protein-coupled receptor.

PLoS ONE, 2013
The evolution of the biogenic amine signalling system in vertebrates is unclear. However, insights can be obtained from studying the structures and signalling properties of biogenic amine receptors from the protochordate, amphioxus, which is an ...
Asha L Bayliss, Peter D Evans
doaj   +1 more source

Neuronal Excitation in the Ventral Tegmental Area Modulates the Micturition Reflex Mediated via the Dopamine D1 and D2 Receptors in Rats

Journal of Pharmacological Sciences, 2003
Involvement of the dopamine D1 and D2 receptors in the ventral tegmental area (VTA) in the micturition reflex was investigated using female Sprague Dawley rats under urethane anesthesia.
Kiyoshi Hashimoto, Tatsuya Oyama, Takahide Sugiyama, Young-Chol Park, Takashi Kurita   +4 more
doaj   +1 more source

Effects of Perioperative Music Interventions on Emotional Outcomes in Children and Adolescents: A Systematic Review and Meta‐Analysis Integrating Developmental Psychology and Music Education Perspectives

Pediatric Anesthesia, EarlyView.
ABSTRACT Objective To evaluate the effects of perioperative music interventions on emotional outcomes (preoperative anxiety, postoperative fear, emergence delirium) and related physiological parameters in children and adolescents undergoing surgery, and to examine potential effect modifiers.
Yuchen Wen, Jinying Han, Jiayin Gao, Jiaqi Lou, Ziyi Xiang   +4 more
wiley   +1 more source

Central dopamine D2 receptors regulate plasma glucose levels in mice through autonomic nerves

Scientific Reports, 2020
Recent evidence suggests that the central nervous system (CNS) regulates plasma glucose levels, but the underlying mechanism is unclear. The present study investigated the role of dopaminergic function in the CNS in regulation of plasma glucose levels in
Hiroko Ikeda, Naomi Yonemochi, Risa Mikami, Manabu Abe, Meiko Kawamura, Rie Natsume, Kenji Sakimura, John L. Waddington, Junzo Kamei   +8 more
doaj   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Gambling disorder in late life: A systematic review of behavioral patterns, clinical correlates, and psychotherapeutic interventions

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Gambling in older adults represents an emerging but still underrecognized mental health concern. Although gambling participation is increasingly observed in later life, the specific psychological, social, cognitive, and biological factors associated with gambling‐related problems in older adults remain insufficiently ...
Graziella C. Prezzavento, Maria C. Quattropani, Vittorio Lenzo, Alberto Sardella, Chiara Franceschini, Giulia Galea, Pasquale Caponnetto   +6 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Severe Lower Limb and Abdominal Edema Associated with Subcutaneous Apomorphine Infusion

Movement Disorders Clinical Practice, EarlyView.
Guillaume Costentin, David Maltête
wiley   +1 more source