Results 81 to 90 of about 147,933 (225)

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium [PDF]

, 2018
Background Dopamine receptors comprise two subgroups, Gs protein-coupled “D1-like” receptors (D1, D5) and Gi-coupled “D2-like” receptors (D2, D3, D4). In airways, both dopamine D1 and D2 receptors are expressed on airway smooth muscle and regulate airway
A Grenader, A Hasbi, A Ricci, A Schmid, C Missale, C Peiser, CA Barlow, CH Kim, CK Billington, CK Billington, DM Aviado, G Di Benedetto, IS Shin, J Chen, JA Bibb, JR Spurzem, K Kurakula, K Mizuta, K Mizuta, KA Neve, KS Song, M Salathe, M Yang, MC Michoud, MG Zizzo, MN Helms, MP Delghandi, MX Shao, N Al-Sawalha, P Calabresi, P Glader, PJ Barnes, R Ozono, R Pivonello, S Gong, S Monterisi, S Naqvi, T Hussain, TA Wyatt, Y Chen, Y Goto   +40 more
core   +5 more sources

Attenuation of Antagonist-induced Impairment of Dopamine Receptors by L-prolyl - L-leucyl-glycinamide [PDF]

, 1988
It has been shown by others that the prenatal treatment of rats with haloperidol, a dopamine D2 receptor antagonist, leads to a permanent reduction in the number of striatal dopamine D2 receptors in adulthood. Conversely, postnatal treatment of lactating
Saleh, Mohamad I.
core   +1 more source

Mechanisms underlying the endogenous dopaminergic inhibition of spinal locomotor circuit function in Xenopus tadpoles [PDF]

, 2016
This work was supported by the Biotechnology and Biological Science Research Council (BBSRC) [grant number BB/J01446X/1].Dopamine plays important roles in the development and modulation of motor control circuits.
Picton, Laurence David, Sillar, Keith Thomas   +1 more
core   +1 more source

D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD

Neurobiology of Disease, 2010
Low doses of psychostimulants produce beneficial behavioral effects in ADHD patients but the mechanisms underlying the response are not understood. Here we use the hyperactive mouse mutant coloboma to identify D2-like dopamine receptor subtypes that ...
Xueliang Fan, Ming Xu, Ellen J. Hess
doaj  

Evidence for dopamine production and distribution of dopamine D2 receptors in the equine gastrointestinal mucosa and pancreas.

PLoS ONE
Insulin dysregulation in horses is characterised by hyperinsulinaemia and/or tissue insulin resistance and is associated with increased risk of laminitis.
Nicolas C Galinelli, Nicholas J Bamford, Melody A de Laat, Martin N Sillence, Patricia A Harris, Simon R Bailey   +5 more
doaj   +1 more source

Dopamine D2 receptor occupancy and cognition in schizophrenia: analysis of the CATIE data.

Schizophrenia bulletin, 2013
INTRODUCTION Antipsychotic drugs exert antipsychotic effects by blocking dopamine D2 receptors in the treatment of schizophrenia. However, effects of D2 receptor blockade on neurocognitive function still remain to be elucidated.
H. Sakurai, R. Bies, S. Stroup, R. Keefe, T. Rajji, Takefumi Suzuki, D. Mamo, B. Pollock, Koichiro Watanabe, M. Mimura, H. Uchida   +10 more
semanticscholar   +1 more source

Characterisation of AmphiAmR11, an amphioxus (Branchiostoma floridae) D2-dopamine-like G protein-coupled receptor.

PLoS ONE, 2013
The evolution of the biogenic amine signalling system in vertebrates is unclear. However, insights can be obtained from studying the structures and signalling properties of biogenic amine receptors from the protochordate, amphioxus, which is an ...
Asha L Bayliss, Peter D Evans
doaj   +1 more source

Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Augments cAMP Accumulation in Striatal Neurons: Evidence for a Gs Linkage to the CB1 Receptor

Journal of Neuroscience, 1997
Cannabinoids act at the CB1 receptor to inhibit adenylate cyclase activity via a pertussis toxin-sensitive G-protein. Within the striatum, CB1 receptors have been shown to be localized on the same neurons as Gi-coupled dopamine D2 receptors.
M. Glass, C. Felder
semanticscholar   +1 more source

Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Proteins Interacting With the Third Cytoplasmic Loop of Dopamine D2 and D3 Receptors

Journal of Pharmacological Sciences, 2010
Among the various dopamine receptors, D2-like receptors (D2R, D3R, and D4R) are characterized by a large third cytoplasmic loop, a short carboxyl-terminal tail, and the ability to activate inhibitory G proteins.
Norifumi Shioda, Yusuke Takeuchi, Kohji Fukunaga   +2 more
doaj  

Central dopamine D2 receptors regulate plasma glucose levels in mice through autonomic nerves

Scientific Reports, 2020
Recent evidence suggests that the central nervous system (CNS) regulates plasma glucose levels, but the underlying mechanism is unclear. The present study investigated the role of dopaminergic function in the CNS in regulation of plasma glucose levels in
Hiroko Ikeda, Naomi Yonemochi, Risa Mikami, Manabu Abe, Meiko Kawamura, Rie Natsume, Kenji Sakimura, John L. Waddington, Junzo Kamei   +8 more
doaj   +1 more source