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Angiotensin receptor blockers and drug–drug interactions
Expert Opinion on Drug Safety, 2005The pharmacokinetic characteristics of the angiotensin receptor blocker class are such that significant drug-drug interactions are unlikely. Moreover, this drug class is devoid of relevant class-specific side effects. These features provide some of the basis for the excellent tolerance of drugs in this class.
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Serotonergic Receptors and Drugs in Hypertension
Pharmacology & Toxicology, 1992Abstract:The possible role of 5‐hydroxytryptamine (5HT) and 5HT‐receptors in hypertension, already suggested by Page in 1954, has been subject to a renaissance of interest owing to the development of antihypertensive drugs which interact with 5HT‐receptors. These drugs, like ketanserin, urapidil and flesinoxan are used as tools to study the role of 5HT
P. van Brummelen +4 more
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2006
This chapter discusses the various mathematical models used to describe and quantify drug response. This begins with consideration of the classical theory which formed the basis of all subsequent models followed by the model of agonism most prevalent in pharmacology at this time, the Black/Leff operational model.
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This chapter discusses the various mathematical models used to describe and quantify drug response. This begins with consideration of the classical theory which formed the basis of all subsequent models followed by the model of agonism most prevalent in pharmacology at this time, the Black/Leff operational model.
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Glycine Receptor Drug Discovery
2017Postsynaptic glycine receptor (GlyR) chloride channels mediate inhibitory neurotransmission in the spinal cord and brain stem, although presynaptic and extrasynaptic GlyRs are expressed more widely throughout the brain. In humans, GlyRs are assembled as homo- or heteromeric pentamers of α1-3 and β subunits. GlyR malfunctions have been linked to a range
Lynch, Joseph W. +3 more
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The classification of drugs and drug receptors in isolated tissues.
Pharmacological Reviews, 1984The major premise of this review is that isolated more effective therapeutic agents for man. In this contissues can be used efıctively to obtain information text, the bias of this paper will be pharmacological in about drugs and drug receptors which transcends species that receptors will be used to gain information about and function. This information,
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Receptor-mediated inotropic drugs
European Heart Journal, 1988Cardiac inotropic activity can be triggered by beta 1-, beta 2- and alpha 1-adrenoreceptors in the heart when stimulated with appropriate agonists. Dopaminergic receptor agonists have little influence on contractile force but the peripheral vasodilatation, improved renal perfusion and enhanced natriuresis mediated by dopaminergic receptor stimulation ...
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Drug–receptor interactions in anaesthesia
BJA Education, 2022J. McDonald, D.G. Lambert
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