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From a single C-mannose to multiple C-mannosyltransferases. [PDF]
J Biol ChemBakker H, Garbers C, Routier FH.
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Erythropoietin and Erythropoietin Receptor
Growth Factors, 1999(1999). Erythropoietin and Erythropoietin Receptor. Growth Factors: Vol. 17, No. 1, pp. 25-35.
P A, Tilbrook, S P, Klinken
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The International Journal of Biochemistry & Cell Biology, 1999
The erythropoietin (epo) receptor is a member of the cytokine receptor family. It is expressed almost exclusively on erythroid precursor cells and controls the development of red blood cells. The epo receptor has no intrinsic kinase activity, but binds intracellular tyrosine kinases to elicit its signals.
P A, Tilbrook, S P, Klinken
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The erythropoietin (epo) receptor is a member of the cytokine receptor family. It is expressed almost exclusively on erythroid precursor cells and controls the development of red blood cells. The epo receptor has no intrinsic kinase activity, but binds intracellular tyrosine kinases to elicit its signals.
P A, Tilbrook, S P, Klinken
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Erythropoietin and Erythropoietin Receptor in Colorectal Cancer
International Journal of Surgical Pathology, 2008Erythropoietin via erythropoietin receptor effectively prevents anemia, giving reasons for a clinical use of erythropoietin in patients with colorectal cancers. However, erythropoietin seems to promote survival of the neoplastic cells in hypoxic environment.
Anna M, Chabowska +5 more
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Immunolocalization of Erythropoietin and Erythropoietin Receptor in Vestibular Schwannoma
Acta Oto-Laryngologica, 2001Vestibular schwannomas constitute approximately 6% of intracranial tumors. Apart from the association with neurofibromatosis-2 (NF-2), where a defect in chromosome 22 has been identified, the pathogenesis of sporadic vestibular schwannomas is largely unknown.
D G, Dillard +5 more
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Seminars in Oncology, 2001
Erythropoietin (EPO) is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. The EPO receptor belongs to the same family of receptors as growth hormone, granulocyte-colony stimulating factor, granulocyte macrophage-colony stimulating factor, and some interleukins.
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Erythropoietin (EPO) is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. The EPO receptor belongs to the same family of receptors as growth hormone, granulocyte-colony stimulating factor, granulocyte macrophage-colony stimulating factor, and some interleukins.
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The human erythropoietin receptor
The International Journal of Cell Cloning, 1992Molecular analysis of the human erythropoietin receptor (EpoR) promises to yield a greater mechanistic understanding of erythropoiesis and disease states that affect red cell production. The cloned receptor molecule is a 66 kDa membrane protein that is structurally related to a large superfamily of haemopoietin/growth factor receptors.
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Physiology and function of the erythropoietin receptor
Current Opinion in Hematology, 1998Interaction between erythropoietin (EPO) and its membrane receptor induces the proliferation and differentiation of erythroid progenitors. Targeted disruption of the EPO receptor (EPOR) gene have clearly demonstrated the importance of the EPO/EPOR system for definitive erythroid cell survival and proliferation; however, in vitro rescue experiments have
A, Yoshimura, H, Misawa
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1995
Abstract Epo receptors are detectable in binding experiments using 125I-epo. Primary erythroid progenitors in the yolk sac, fetal liver, bone marrow and spleen express small numbers of receptors, as do megakaryocytes (300-1000 per cell) (Youssoufian et al. 1993).
D J Hilton, S S Watowich
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Abstract Epo receptors are detectable in binding experiments using 125I-epo. Primary erythroid progenitors in the yolk sac, fetal liver, bone marrow and spleen express small numbers of receptors, as do megakaryocytes (300-1000 per cell) (Youssoufian et al. 1993).
D J Hilton, S S Watowich
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The role of erythropoietin and erythropoietin receptor in malignant laryngeal tumors
Medical Hypotheses, 2013Erythropoietin (Epo) is a glycoprotein hormone responsible for erythropoiesis. Its effect is realized by binding erythropoietin receptor (EpoR) expressed on erythroid progenitor cells. Hypoxia is the main stimulus for the secretion of erythropoietin. Anemia is an independent negative prognostic factor for survival in patients with malignant diseases ...
Vukelić, Jelena +4 more
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