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Interleukin-6 in hemolytic anemias: from inflammatory pathways to therapeutic targeting. [PDF]
Front ImmunolZhao M, Yu X.
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Rethinking EPO: A Paradigm Shift in Oncology? [PDF]
Cancers (Basel)Ferrero JM +4 more
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Two Cases of Giant Uterine Leiomyomas With Myomatous Erythrocytosis Syndrome Treated by Laparoscopic Hysterectomy. [PDF]
CureusAimoto N, Matsumoto T, Tsuda Y, Yumi H.
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Erythropoietin and Erythropoietin Receptor
Growth Factors, 1999(1999). Erythropoietin and Erythropoietin Receptor. Growth Factors: Vol. 17, No. 1, pp. 25-35.
P A, Tilbrook, S P, Klinken
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The International Journal of Biochemistry & Cell Biology, 1999
The erythropoietin (epo) receptor is a member of the cytokine receptor family. It is expressed almost exclusively on erythroid precursor cells and controls the development of red blood cells. The epo receptor has no intrinsic kinase activity, but binds intracellular tyrosine kinases to elicit its signals.
P A, Tilbrook, S P, Klinken
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The erythropoietin (epo) receptor is a member of the cytokine receptor family. It is expressed almost exclusively on erythroid precursor cells and controls the development of red blood cells. The epo receptor has no intrinsic kinase activity, but binds intracellular tyrosine kinases to elicit its signals.
P A, Tilbrook, S P, Klinken
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Erythropoietin and Erythropoietin Receptor in Colorectal Cancer
International Journal of Surgical Pathology, 2008Erythropoietin via erythropoietin receptor effectively prevents anemia, giving reasons for a clinical use of erythropoietin in patients with colorectal cancers. However, erythropoietin seems to promote survival of the neoplastic cells in hypoxic environment.
Anna M, Chabowska +5 more
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Immunolocalization of Erythropoietin and Erythropoietin Receptor in Vestibular Schwannoma
Acta Oto-Laryngologica, 2001Vestibular schwannomas constitute approximately 6% of intracranial tumors. Apart from the association with neurofibromatosis-2 (NF-2), where a defect in chromosome 22 has been identified, the pathogenesis of sporadic vestibular schwannomas is largely unknown.
D G, Dillard +5 more
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Seminars in Oncology, 2001
Erythropoietin (EPO) is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. The EPO receptor belongs to the same family of receptors as growth hormone, granulocyte-colony stimulating factor, granulocyte macrophage-colony stimulating factor, and some interleukins.
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Erythropoietin (EPO) is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. The EPO receptor belongs to the same family of receptors as growth hormone, granulocyte-colony stimulating factor, granulocyte macrophage-colony stimulating factor, and some interleukins.
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The human erythropoietin receptor
The International Journal of Cell Cloning, 1992Molecular analysis of the human erythropoietin receptor (EpoR) promises to yield a greater mechanistic understanding of erythropoiesis and disease states that affect red cell production. The cloned receptor molecule is a 66 kDa membrane protein that is structurally related to a large superfamily of haemopoietin/growth factor receptors.
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