Results 71 to 80 of about 19,757 (238)

The Cellular Biology of Erythropoietin Receptors

open access: yesThe Oncologist, 2003
Abstract Learning Objectives After completing this course, the reader will be able to: Explain the structure and functions of erythropoietin. Distinguish the multiple activities of erythropoietin in the human body. Recognize the potential role of erythropoietin receptors in targeting
openaire   +2 more sources

Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain

open access: yesActa Neuropathologica, 2001
Using immunohistochemistry, expression of erythropoietin (EPO), a hypoxia-inducible neuroprotective factor, and its receptor (EPOR) were investigated in human brain tissue after ischemia/hypoxia. Autopsy brains of neuropathologically normal subjects were compared to those with ischemic infarcts or hypoxic damage.
Siren, A. L.   +5 more
openaire   +3 more sources

Prognostic impact of iron deficiency in new‐onset chronic heart failure: Danish Heart Failure Registry insights

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1346-1357, April 2025.
Abstract Aims Iron deficiency (ID) is prevalent in chronic heart failure (HF) but lacks a consensus definition. This study evaluates the prevalence and the prognostic impact of ID using different criteria on all‐cause and cardiovascular mortality, as well as first hospitalization for HF in patients with new‐onset chronic HF.
Abdullahi Ahmed Mohamed   +12 more
wiley   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

open access: yesFood Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo   +8 more
wiley   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

Inflammation and Erythropoietin Resistance in Chronic Kidney Disease: A Cross‐Sectional Study of C‐Reactive Protein and Anemia in Hemodialysis Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study examined the role of inflammation in anemia among patients with chronic kidney disease on maintenance hemodialysis. Elevated C‐reactive protein (CRP) levels were associated with reduced iron availability, lower hematocrit, and increased erythropoietin requirements.
Collince Odiwuor Ogolla   +3 more
wiley   +1 more source

ephrin ligands and Eph receptors show regionally restricted expression in the developing palate and tongue

open access: yesFrontiers in Physiology, 2016
The Eph family receptor-interacting (ephrin) ligands and erythropoietin-producing hepatocellular carcinoma (Eph) receptors constitute the largest known family of receptor tyrosine kinases.
Guilherme Machado Xavier   +2 more
doaj   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

open access: yesOrgan Medicine, EarlyView.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

open access: yesOrgan Medicine, EarlyView.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai   +8 more
wiley   +1 more source

Comparative analysis of the JAK/STAT signaling through erythropoietin receptor and thrombopoietin receptor using a systems approach

open access: yesBMC Bioinformatics, 2009
Background The Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathway is one of the most important targets for myeloproliferative disorder (MPD).
Lee Eunjung   +4 more
doaj   +1 more source

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